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J Peyri

Publications and source records attributed to J Peyri.

18 recordsLinked to original sources

Calcinosis cutis following liver transplantation: a complication of intravenous calcium administration.

Calcinosis cutis may be a complication of administration of intravenous calcium solutions. We report four patients who developed calcinosis cutis following orthotopic liver transplantation, all of whom had received calcium chloride solutions intravenously during surgery. There was no evidence of extravasation of the solutions. A gradual improvement of the lesions was seen in the subsequent months. This complication of intravenous calcium infusions is probably related to the large amounts of blood-derived products and of calcium salts administered during surgery.

Adult

Quantitative and morphometric analysis of Langerhans cells in non-exposed skin in renal transplant patients.

Renal transplant recipients have a high incidence of cutaneous complications such as neoplasia and viral or fungal infections. Morphologic alterations of epidermal Langerhans cells (LC) have furthermore been described in these patients. Since these changes have been mainly found in sun-exposed skin, a direct effect of immunosuppressive therapy remains a matter of discussion. A quantitative and morphometric study of epidermal LC in non-exposed skin was performed in 28 renal transplant patients (RTP). RTP were divided in two groups according to immunosuppressive treatment: group A; azathioprine + prednisone (14 cases) and group B; cyclosporine + prednisone (14 cases). Twenty sex-age matched non-immunosuppressed patients acted as controls (group C). Epidermal sheets were obtained by incubation in EDTA and stained for ATPase activity and with the monoclonal antibody T6 (CD1) using the avidin-biotin peroxidase method. Langerhans cells were counted using a calibrated graticule (400x) and expressed as the mean number of LC/mm2. The mean area of the LC and the number of primary dendrites (pd) and secondary dendrites (sd) were determined with a morphometer adapted to an Apple II computer. The mean number of positive cells in controls was: ATPase, 677 +/- 157; T6, 695 +/- 164. Patients in group A had the maximum reduction in both ATPase and T6 LC density (ATPase, 339 +/- 142; T6, 402 +/- 194). Patients in group B had an intermediate reduction in the number of LC (ATPase, 494 +/- 121; T6, 529 +/- 112).(ABSTRACT TRUNCATED AT 250 WORDS)

Adenosine Triphosphatases

A significant geographical area for the study of the epidemiological and ecological aspect of Mediterranean sporothricosis.

Two cases of sporothricosis originating from the same geographical area (Province of Barcelona) are described, including the circumstances of infection and the isolation of a wild strain of Sporothrix schenckii at the same locality. This finding could classify this particular area as a zone of interest in the epidemiological and ecological study of the mediterranean sporothricosis.

Adolescent

[Steatocystoma multiplex].

A 50 years old male patient with numerous cysts over the scalp since the age of 48 is reported in whom the lesions appeared abruptly in two crops in a short period of time. Several biopsies were done showing most of them the typical histologic characteristics of steatocystoma multiplex. The authors remark in this patient the nonhereditary character of the condition, appearing late in life with an eruptive character and strict limitation over the scalp, features that are not often seen in steatocystoma multiplex. The authors pointed out that not all the cysts showed the typical histopathological picture of the disease. Therefore several biopsies must sometimes be done, before the diagnosis is established.

Epidermal Cyst

[Multiple eccrine-pilar hamartoma].

Two cases with acquired lesions on the face and tendency to spread are reported. The unusual lesions have the appearance between millium and atrophodermia vermiculate and the histology presents features of syringoma and trichoepithelioma making this hamartoma unclassifiable. Cases with similar characteristics are discussed.

Adult

[Incapacitating pansclerotic morphea in childhood].

An 8-year old boy with generalized morphea involving all levels of the skin and soft tissues with disabling course, policlonal elevation of gammaglobulins and peripheral eosinophilia is examined. Neither Raynaud's disease nor sings of systemic scleroderma were present. The biopsy specimen showed thickening and hyalinization of collagenous tissue with moderate lymphocytic and plasma cell infiltration, mainly in the subcutaneous region and fascia. A diagnosis of Disabling Panscleroti morphea of children (Díaz-Pérez et al., 1980) was done. With this case and others reported in the literature, the authors compare this peculiar picture with the usual type of morphea, systemic scleroderma and eosinophilic fasciitis.

Antibodies, Antinuclear

Idiopathic guttate hypomelanosis.

Idiopathic guttate hypomelanosis is usually associated with guttate hyperkeratosis, xerosis, and lentiginosis not related to the patient's age. Histologically, hypopigmented macules show remarkably decreased melanin, decreased DOPA-oxidase activity and a decreased number of melanosomes in the melanocytes with predominance of Stages I and II and small sizes. The epidermis is always atrophic. When scales are removed by scraping, hyperkeratotic lesions show, clinically and histologically, variable degrees of hypomelanosis; thus suggesting a relationship with the hypopigmented macules. These data suggest that idiopathic guttate hypomelanosis is the result of an early aging of the skin.

Adult

[Becker's nevus associated with a smooth muscle hamartoma].

A new case of Becker's nevus associated with smooth muscle hamartoma is reported. This is the third case reported in the literature. The different associations reported in the Becker's nevus give support to the mesenchymal-epithelial interactions.

Adult

[Gorham's disease].

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Adult