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Biomedical subjects

J Philips

Publications and source records attributed to J Philips.

60 records · Page 4Linked to original sources
PubMed1977

Partial deletion of long arm of chromosome 11: del (11) (q23).

The cytogenetic analysis of an infant with multiple congenital anomalies revealed a small deletion of the long arm of one No. 11 chromosome: 46,XX,del(11)(q23). The main clinical manifestations included: ocular colobomata, absent philtrum, severe congenital heart disease, contractures of the large joints and skin pigmentation. Both parents showed a normal chromosome constitution. In comparison to the previously reported cases of 11q-, the patient presented here had more severe congenital anomalies. The correlation of the size of the deletion, and the location of the break, with the physical findings is discussed.

Abnormalities, Multiple↗
PubMedDate not supplied

Antibiotic resistance of Escherichia coli in fecal samples of healthy people in two different areas in an industrialized country.

Fecal samples of 310 healthy persons, from two populations from different areas in the Netherlands, were examined for the presence of Escherichia coli resistant to ampicillin, tetracycline, sulfamethoxazole, trimethoprim and nitrofurantoin. High prevalences of resistance were found in both populations, ranging from 28% for trimethoprim to 89% for ampicillin. The percentages of the fecal samples with a dominantly resistant E. coli flora (> 50% resistance) were distinctly lower, ranging from 1% for nitrofurantoin to 21% for tetracycline. No significant differences in the level of resistance were observed between these two comparable populations in two different areas. The susceptibilities to 11 antimicrobial agents of 456 at random isolated E. coli were determined. The percentages of resistance varied widely: from 80% for chloramphenicol to 9% for nitrofurantoin. Only 19% of the isolates were susceptible to all antibiotics tested and 14% were resistant to more than four of the agents tested. Great differences in resistance rates between the two populations examined were seen for chloramphenicol (80% to 41%) and trimethoprim (16% to 36%). The results of this study underscore the presence of a human reservoir of antibiotic resistant microorganisms.

Adolescent↗
PubMedDate not supplied

Fine needle aspiration cytology of an unusual presentation of leukemia. A case report.

A 17-year-old active sportsman presented three weeks after a football injury with pain in the right hip and back. Osteomyelitis was the initial clinical diagnosis. A full blood count and erythrocyte sedimentation rate were normal. Fine needle aspiration of the anterior inferior iliac spine showed the presence of numerous blasts. This case represents an unusual presentation and method of diagnosis of acute leukemia.

Adolescent↗