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J Pike

Publications and source records attributed to J Pike.

38 records · Page 3Linked to original sources
PubMedDate not supplied

Chemistry of cement burns: pathogenesis and treatment.

Two brief cases are presented describing burns resulting from exposure to cement and its components. Of particular interest is the etiology of such burns. Do they result from a high pH solution in contact with the skin under abrasive conditions for an undetermined period of time, or are they a consequence of possible allergic reactions to chromium or chromates? Another possible factor that has been largely unexplored is the role of the calcium ion--the other principal ionic species with which the skin is in contact. Much has been written about its role in membrane transport and other physiologic processes.

Adult↗
PubMedDate not supplied

Partial sleep deprivation reduces natural killer cell activity in humans.

Sleep disturbance, measured by either subjective report or electroencephalographic (EEG) assessment of sleep, correlates with a reduction of natural killer (NK) cell activity in major depression. To test whether sleep loss independent of mood disturbance alters daytime values of cellular immune function, the effect of late-night partial sleep deprivation on NK cell activity was studied in 23 medically and psychiatrically healthy male volunteers. After a night of sleep deprivation between 3 and 7 AM, NK cell activity was reduced in 18 of the 23 subjects with average lytic activity reduced significantly (p < .01) to a level 72% of the mean of three separate baseline values. After a night of resumed nocturnal sleep, NK cell activity had returned to baseline levels. These data implicate sleep in the modulation of natural immunity and demonstrate that even modest disturbances of sleep produce a reduction of NK cell activity.

Adult↗