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Biomedical subjects

J Pimentel Leo

Publications and source records attributed to J Pimentel Leo.

3 recordsLinked to original sources

[Lung sarcoidosis following instillation of mitomycin C in the urinary bladder].

Intravesical prophylaxis against recurrence of urinary bladder carcinomas using mitomycin C (MMC) has proved to be and effective treatment with few side effects. Previously only two cases of lung toxicity after instillation of MMC into the urinary bladder has been described. We report a 65-year-old man in whom lung sarcoidosis occurred after intravesical administration of MMC. This association has not been reported to date. The clinical picture and the pathogenesis of this lung disease are discussed.

Administration, Intravesical↗

[Familial pseudoxanthoma elasticum].

Pseudoxanthoma elasticum is a genodermatosis caused by a change in elastic fibers but with a non well defined biochemical correlate. Its prognosis depends upon the degree of visceral involvement. The appearance of cutaneous lesions allows an early diagnosis. We report here three sisters aged 23, 21, and 19 years with pseudoxanthoma elasticum who had typical cutaneous and retinal lesions. The clinical diagnosis was confirmed by a cutaneous biopsy. To note the high diagnostic yield and minimal morbidity of the cutaneous biopsy for diagnosing this disease.

Adult↗

[Pleomorphic bladder rhabdomyosarcoma in an adult male. Apropos of a case].

We report on a 45-year-old male patient with a mesodermal tumor localized in the striated muscle of the bladder wall. The histopathologic analysis revealed a stage I pleomorphic tumor. The clinical and histologic features of this uncommon tumor type are described. Treatment by partial surgery and adjuvant chemo- and radiotherapy (CMT + XRT) have achieved good results. The patient is asymptomatic 44 months thereafter.

Combined Modality Therapy↗