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Biomedical subjects

J Pitfield

Publications and source records attributed to J Pitfield.

6 recordsLinked to original sources
PubMed1983

Contrast media and bronchospasm: a study with iopamidol.

Conventional radiological contrast media given intravenously are known to produce bronchospasm in the majority of patients, even though this is rarely clinically apparent. We have found that this phenomenon is much less pronounced with the new, low-osmolality contrast medium iopamidol. If the mechanism underlying the clinically silent bronchospasm observed with the conventional media is the same as that underlying the occasional life-threatening or fatal bronchospasm, then this observation is of considerable importance.

Bronchial Spasm↗
PubMed1983

Isomeric purity and supersaturation of iopamidol.

We have found that iopamidol 370 mg I/ml solutions may be greatly supersaturated and iopamidol 300 mg I/ml solutions slightly supersaturated at 4 degrees C and at 25 degrees C. The solubility and degree of supersaturation probably depend on the isomeric purity of the preparation. Some possible implications are discussed.

Contrast Media↗