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Biomedical subjects

J Planitzer

Publications and source records attributed to J Planitzer.

At least 19 recordsLinked to original sources
PubMed1993

Triple-dose versus standard-dose gadopentetate dimeglumine: a randomized study in 199 patients.

To investigate the safety, patient tolerance, and efficacy with 0.3 mmol/kg gadopentetate dimeglumine in magnetic resonance (MR) imaging of the central nervous system (CNS), a phase 3 trial was conducted in 199 patients with suspected CNS lesions. Patients received either 0.1 or 0.3 mmol/kg gadopentate dimeglumine (injection time, 15 seconds and 45 seconds, respectively). T1- and T2-weighted spin-echo sequences were performed at either 0.5 T or 1.5 T. In 80 patients with enhancing brain lesions, contrast-to-noise ratios (C/Ns) were calculated, and lesion-to-brain contrast was evaluated visually. Six patients (6%) in each dose group reported adverse events. Eight adverse events occurred with 0.1 mmol/kg and seven with 0.3 mmol/kg. Vital signs and laboratory values did not change significantly. C/N (P < .05) and visual assessment ratings were higher with 0.3 mmol/kg than with 0.1 mmol/kg. According to these preliminary results, 0.3 mmol/kg gadopentetate dimeglumine is safe and well tolerated when administered at approximately 1 mL/sec.

Adult↗
PubMed1990

[Typical CT findings with the intrathecal infusion test in post-traumatic disorders of cerebrospinal fluid dynamics].

Simultaneous computer tomographic and cerebrospinal fluid dynamics examinations in patients with high-pressure hydrocephalus, normal pressure hydrocephalus and cerebral atrophic processes are presented and discussed. Exclusive CT and MR examinations do not allow a differentiation of patients with normal pressure hydrocephalus and patients with cerebral atrophy. In the simultaneous examinations the morphological substrate during the intrathecal infusion test is represented.

Adult↗
PubMed1989

[Nosologic classification of Fazio-Londe disease].

The observation of a progressive bulbar paralysis with lethal exit in a 20 years old patient, whose mother had died in the age of 29 years after a similar course of disease, is coordinated as Fazio: Londe-disease. But peculiarities are mentioned, that refer to traits of the special form of progressive bulbar paralysis described by Kennedy and of Kugelberg-Welander-disease. A genetic basis of variability is supposed.

Adult↗
PubMed1989

[Neuroradiologic diagnosis of elongated spinal tumors].

Elongated spinal space-occupying lesions are infrequent but not rare. They are found at all ages, most frequently in the thoracic spinal canal and are primarily of gliomatous origin. A survey of our cases from the last 25 years shows the enormous progress in the diagnosis of such processes. This applies to technical quality as well as improved diagnostic information of modern methods and significantly less discomfort to the patient. In the case of suspected space-occupying lesions, a consecutive diagnostic program is recommended, that implies first conventional radiographs of the structure of the spine (including tomography if necessary) followed by myelography with modern positive contrast media. Myelography should be combined with CT. Plain CT-scans can demonstrate hypodense or calcified tumours. MRT provides essential additional information by three dimensional imaging and the corresponding signal processing techniques. With increasing MRT-capacities and improving image quality medullary tumours will primarily investigated with this method. The relations between multiple intramedullary cavities can be explored by endomyelography before drainage.

Adolescent↗
PubMed1989

[A CT localization frame--an improved method for preoperative localization of intracranial processes].

A new CT localization equipment for cerebral processes is presented. As compared to the methods used until now it offers the advantage that no direct marking on the shaven skull must be provided. The parameters resulting during the CT examination with applied localization frame enable the preoperative localization at any desired time. A precondition is the use of an identical device by the surgeon. The use of the methods is explained.

Brain Neoplasms↗
PubMed1989

[Grading of brain tumors using computer-assisted analysis of CT images and anamnestic data].

For the classification of various brain tumours data from 139 patients with histologically proven diagnosis were used. With linear discriminant analysis and hierarchic classification of clinical and anamnestic data and features obtained by Walsh-transformation of image data presently 7 classes of tumours are differentiated with an estimated classification rate of 85% and reclassification rate of 92%.

Brain Neoplasms↗
PubMed1986

[Dorsolateral thalamic infarct syndrome with therapeutically modifiable pain crises].

The Controlateral Pain Flexor Reflex (CPFR) is demonstrated by a case study of a thalamic syndrome with a typical thalamic hand, thalamic foot, and thalamic pain crisis. Mechanical triggering by a painful irritation on the healthy hand side leads to a stronger motoric-nocifensic reflex response of the contralateral extremities. On the other hand the healthy person would develop an ipsilateral nocifensic response only. In the case reported here, the electrically evoked CPFR led to the same result, and simultaneously caused disappearance of the thalamic pain, since this kind of management represents therapeutical approach via the endorphin system. In respect of the pathophysiological basis of the thalamic modified nocifensic reflex response, we are inclined to believe that painful stimulation evokes an accentuated flexor reaction if the thalamic-controlled influences are omitted by a lesion of the specific nuclei.

Adult↗
PubMed1985

[Irreversible cerebral function loss (so-called brain death). Further experiences in diagnostic procedures].

Analyzing international 15 years experiences the authors characterize the present situation of knowledges and practical possibilities concerning brain death diagnostics. It must be differentiated between generally accepted obliging criterions and the remaining space of responcibility of the neurologist, who is acting as a member of a brain death commission. In this frame procedures have to be chosen, which allow to diagnosticate without any doubt and as early as possible. Further developmental possibilities are shown.

Brain Death↗
PubMed1985

[Computer tomography studies in irreversible cerebral function loss (brain death)].

12 patients, whose neurological findings had induced the procedure of brain death determination, and further 4 young children were examined correspondently by special CT methods. In conclusion cranial computerized tomography as a non-invasive method seems to be useful alternatively beside cerebral angiography for the documentation of cerebral circulation arrest.

Adolescent↗
PubMed1984

[Value of computer tomography in the diagnosis of impression fractures of the cranial vault].

There are only few statements about the validity of computed tomography for the identification of impression fractures of the skull cap. The diagnostic information of roentgenograms without contrast medium and computed tomograms of a total of 15 patients were evaluated and compared. It was found that computed tomography was slightly superior to conventional X-ray examinations with respect to the diagnostic accuracy. Exact localisation, size, shape, and position of the bony impressions can be better appraised by the assessment in several axial CT section planes. The simultaneous consideration of the sequelae of the intracranial traumata by computed tomography enables a complete assessment of the craniocerebral trauma. The appropriate combination of conventional X-ray diagnosis with computed tomography should lead to an optimum diagnostic information also for these clinical pictures.

Adolescent↗