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Biomedical subjects

J Plank

Publications and source records attributed to J Plank.

At least 19 recordsLinked to original sources
PubMed1992

Developmental expression of the 3-fucosyl-N-acetyl-lactosamine/CD15 epitope by an olfactory receptor cell subpopulation and in the olfactory bulb of the rat.

In the olfactory epithelium a subpopulation of receptor cells were CD15 (3-fucosyl-N-acetyl-lactosamine)-positive at their somata and their processes. Cytomorphology and location implied their mature character. The labeled neurons were associated with olfactory cilia and showed a unique distribution within the olfactory epithelium and a remarkable numerical change during postnatal ontogeny. The axons of the marked olfactory receptor cells possibly play a role in guiding other axons to their appropriate targets in the olfactory bulb. In the olfactory bulb immunoreactivity was predominantly found in the glomerular and in the external plexiform layer and showed an age-related shift from the superficial to the deep layers.

Animals↗
PubMed1992

Squamous cell carcinoma of the penis. Analysis of 24 cases.

The authors evaluated retrospectively 24 cases of spinocellular carcinoma of the penis, trying to detect aetiological carcinogenic factors of the disease. Phimosis persisting since childhood was reported by ten men, whereby in five of them circumcision was performed during puberty. The duration of symptoms up to the time of biopsy and histological verification of differentiated spinocellular carcinoma of the penis varied from one month to thirteen years. Eight patients (33.3%) belonged to category T1, 8 (33.3%) to T2 and 8 (33.3%) to T3. Fifteen tumours (62.5%) were G1, 5 (20.8%) G2 and 4 (16.7%) G3. In 5 men print cytology was negative.

Carcinoma, Squamous Cell↗
PubMed1991

[Developmental trends in pathology].

The paper calls attention to the main problems of pathology in Czechoslovakia. There is a need of performance standards for quality assessment and for the health insurance.

Autopsy↗
PubMed1988

[Classification of the lung conditions in cases of perinatal death].

Comparability of morphological lung findings depends on the greatest possible consistency in assessment and verbal definition. It is for that purpose that a classification of perinatal pulmonary morphology is proposed, based on latest knowledge in foetal and paediatric pathology and established with due consideration of findings from clinical and physiological research as well as of the author's own experience. The findings have been subdivided into five main groups, each of them with several sub-groups, and have been pathomorphologically so characterised that the new classification can be easily used in prosector practice.

Female↗
PubMed1987

[Effect of dietary zinc deficiency on vitamin A and alpha-tocopherol metabolism in the rat].

In order to study the effect of alimentary zinc deficiency on vitamin A and alpha-tocopherol metabolism, weaned, male Sprague-Dawley rats with a mean weight of 48 g were divided into three groups. Zinc depletion animals (n = 7) were provided a half-synthetic, casein-based diet with a zinc concentration of 1.3 ppm; the pair-fed (n = 7) and ad libitum-fed (n = 6) control animals were given a diet containing 96 ppm zinc. After 24 days, the serum zinc level for depletion animals was 80% lower than the level for the two control groups, although the vitamin A, beta-carotine and tocopherol concentrations in deficiency animals and in pair-fed control animals did not differ significantly from one another. In comparison with adlibitum-fed control rats, however, vitamin A and beta-carotine concentrations in depletion and pair-fed animals were elevated. The zinc concentration in livers of deficiency animals was reduced only in comparison to the value for pair-fed control animals, while the vitamin A, beta-carotine and alpha-tocopherol concentrations in livers of zinc-deficient animals were reduced in comparison to the values for both of the control groups. Nevertheless, these changes are less likely a result of zinc deficiency per se, but rather are more likely a result of the lowered feed intake during zinc deficiency and the reduced growth.

Animals↗
PubMed1986

[Weight of major organs in eutrophic and hypotrophic neonates].

Brain, heart, liver, and kidney weight are analyzed from autopsy material derived from 236 appropriate for gestational age and 92 small for gestational age newborns. Average organ weight was calculated by gestational age in weeks and by birthweight in 100 gram divisions. The correlation between gestational age and organ weight was, for all organs, significantly different for the small for gestational age newborns compared to appropriate for gestational age newborns. Birthweight to individual organ weight correlations were virtually the same for appropriate for gestational age and small for gestational age newborns. The table of organ weights by 100 gram subdivisions may serve as a basis for determining whether growth of an organ was normal or retarded.

Autopsy↗
PubMed1985

[Biometric data of normotrophic neonates].

Gestation age of a neonate could be estimated approximately by a pathologist according to some macroscopical features. In addition to the weight of large organs the authors studied weight of other organs and some biometrical data in a group of 84 normotrophic neonates. Regressive analysis gave information about the growth trend of organs; compared with tables it enabled to find out the growth retardation of a neonate or his single organ. The span of fingers represented a precise statistical figure for the estimation of gestation age in addition to the weight of organs.

Anthropometry↗
PubMed1985

[Diagnosis and classification of pulmonary findings in neonates].

Developmental phases could be defined in neonatal lung tissue fixed in situ or in an ordinary way: glandular lung, canalicular lung with simple tubes covered by cuboid epithelial cells, alveolar lung with usual complicated structure. Canalicular lung could manage the blood saturation which depends on the number of capillaries. There was a different picture of alveoli filled with fluid or air. Hyaline membranes, always occurring in fluid-filled alveoli, represented a barrier for drainage of intraalveolar fluid. Step-wise inflation of lung enabled a histomechanical examination giving lately "functional" figures. They showed a poor functional readiness as well as a quick postnatal adaptability of immature lung. Pressure-volume curves correlated with histological maturity and pathological finding offered a more comprehensive explanation of clinicopathological mechanisms.

Fetal Organ Maturity↗
PubMed1985

[Evaluation of kidney maturity in neonates].

Morphometric analysis of glomeruli allows to estimate renal maturity or find out an accidental retardation of growth. A simpler estimation of the number of yalers formed by immature glomeruli is less time-consuming. Final diagnosis of pathologist should include this estimation. An intense growth of glomeruli does not start before glomerular lobulation concurring with an increase of capillary lumina in a glomerular square unit. So lobulation expresses generally the maturity of glomeruli.

Fetal Organ Maturity↗
PubMed1985

[Criteria for neonatal maturity. Conclusions for practice].

The evaluation of neonatal maturity is an important condition for interpretation of pathologist's findings. Weight of organs and other biometrical data, histological evaluation of maturity in various organs and rebuilding of circulation give objective morphological criteria of maturity as well as isolated retardation of growth or development.

Fetal Organ Maturity↗
PubMed1984

[Brain weight in relation to the maturity of the newborn infant].

Average cerebral weights were calculated in correlation to the age of gestation and birth weight in 84 hypotrophic and 219 normotrophic neonates. Correlation of cerebral weight and gestation age was significantly different in the both groups, correlation of cerebral weight and birth weight was parallel. Cerebral growth trend can be estimated in routine autopsies according these results.

Birth Weight↗