[Conservative therapy for spondylolisthesis].
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Biomedical subjects
Publications and source records attributed to J Plath.
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In this case, we present a 5-year follow-up of a 3-fault-affected primary leiomyosarcoma of the distal femur (spontaneous fracture treated by osteosynthesis; marginal resection; stump fracture after adequate trauma) with an extended local recurrence but without metastasis.
Thirty-three X-press cementless stems (Depuy) manufactured according to standardized X-rays were inserted from 1992 to 1994. The patients' mean age was 49 (range 15-79) years with a mean follow-up of 32 (+/-6) months. A characteristic radiographic pattern of aseptic loosening with erosion of the medial cortex by the tip of the stem occurred in 28 patients and a valgus shift of the implant in 14 cases. A radiolucent line with increased sclerosis below the tip (zone Gruen 4) was observed in 17 cases. Four stems were revised due to histologically confirmed aseptic loosening. Biomechanical investigation of one of the revised stems with the typical pattern of valgus angulation and medial cortex erosion included photoelasticity and finite-element analysis. The intertrochanteric fit and fill obviously resulted in an unfavorable distribution of contact areas, including peaks of high stress on the medial tip of the stem. These experimental findings are even evident for a postulated rotational stability. The clinical and radiographic results of the cementless X-press stems do not seem to support the fixation concept of intertrochanteric fit and fill of femoral components.
We report the unusual complication of focal necrotizing skin lesions accompanied by moderate thrombocytopenia in a female patient undergoing thromboprophylaxis with low-molecular-weight heparin after total knee arthroplasty. Heparin-induced thrombocytopenia was suspected and confirmed using the heparin-induced platelet activation assay. The skin lesions improved gradually after the discontinuation of heparin application. In addition to the description of this exceptionally rare adverse effect of low-molecular-weight heparin, a brief discussion of previously reported cases is provided.
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Pelvis radiographs of 47 children with slipped capital femoral epiphyses (SCFE) and 24 without a hip disorder were reviewed in a retrospective study by four readers to determine the skeletal age by the Oxford method. 72% of the children suffering from SCFE had a body weight above the standard level but a normal body height at the time of diagnosis. The mean chronologic age was 3 years higher than the skeletal age determined by the Oxford-score. The linear regression analyses showed that children with SCFE have had a skeletal maturation delay in comparison with the normal group at the beginning of the age period in question. This deficiency became greater as chronologic age increased. All children with the SCFE disease showed a nearly uniform skeletal age clearly below the bone age standard irrespective of their chronologic age. These results, in connection with obesity in most cases, support the idea of hormonal disorders with delayed skeletal maturation development in the aetiology of SCFE disease.