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Biomedical subjects

J Pleva

Publications and source records attributed to J Pleva.

14 recordsLinked to original sources

The dental amalgam issue. A review.

Using an interdisciplinary approach, the current position in the dental amalgam controversy and the potential impact of amalgam mercury on human health are reviewed. Aspects of materials science, corrosion, mercury exposure, toxicology, neurology and immunology are included. New data on mercury exposure from corroded amalgam fillings in vivo are presented. The exposure can reach levels considerably over known threshold limit values. Also, measurements of mercury absorption from intraoral air are presented. The vital importance of avoiding a galvanic amalgam-gold coupling is emphasized. The symptomatology of a disabled patient, who recovered after amalgam removal, has been included. It is concluded that discussion of the dental amalgam issue has suffered from the lack of an interdisciplinary approach. It would be wise to learn from the lesson of acrodynia, and consider amalgam mercury among other possible factors in neurological and immunological diseases of unclear etiology.

Dental Amalgam

[Microbiological quality of mechanically deboned beef].

Microbial quality of mechanically deboned beef (MDB), which was obtained by the discontinuous hydraulic horizontal separator, type Inject-Star (firm LASKA, Austria), was analyzed for the presence of indicatory microorganisms (coliforms and enterococci), pathogenic and conditionally pathogenic microorganisms. The basic microbial parameters have been determined separately for MDB of 1st, 2nd degrees as well as for average daily samples from one collecting vessel. Apart from it, also a raw material (beef from flesh bones intended for separation) and salt MDB after 24 hrs storing in chiller before working it into meat products were examined by the same way. From our results it follows that the number of all microorganisms observed in MDB of 1st degree was lower than that of 2nd degree. During the separation process the increase of microbial parameters compared with those in initial raw material occurred by 1-2 radices and following subsequent salting and storing in chiller there was a repeated decrease by 1 radix (with exception of the number of Staphylococci remaining unchanged). The change in the amount of microflora present was also influenced by season--in summer there was an increase by about 1 radix. From the view point of food hygiene the finding of salmonellas and the presence of large number of Staphylococci including Staphylococcus aureus on average 10(5).g-1 as well as the presence of wide extent of conditionally pathogenic microorganisms from the family of Enterobacteriaceae, especially from genera Proteus, Providencia, Morganella and Citrobacter are of great importance.

Animals

[Occurrence of PSE and DFD meat in swine slaughtered under emergency conditions].

The occurrence of qualitative changes in meat was studied in a set of 1008 pigs slaughtered in four sanitation slaughter houses for the period of 12 months. PSE meat was found in 206 pigs (20.43 per cent) and DFD meat only in 9 pigs (0.89 percent) of the total number of pigs examined. The rule was applied that the defect should be demonstrated by two of three commonly used parameters (the pH value, colour and water loss by dripping). The highest occurrence of qualitative changes in meat of PSE type was registered in the group of animals with a defect of the respiratory organs (32.53 per cent) and the lowest in animals with diseases of sexual organs, including parturition complications (5.00 per cent). A similar trend was recorder even in the DFD meat occurrence. As to the seasons, the highest percentage of occurrence of PSE defects was in July and August (35.41 and 29.06 per cent) and the lowest (8.64 and 10.97 per cent) in March and January. The actual disease is proved to be only one of the secondary stress to induce the PSE meat formation.

Animals

[Dynamics of methemoglobin levels in the blood of calves in relation to the ingested quantity of nitrates and the transrenal transport of nitrates].

Changes of methaemoglobin levels were investigated in the blood of suckling calves. Transrenal passage of nitrates was determined in dependence on the ingested amount of nitrates. The experiments were conducted under defined husbandry conditions; no excessive nitrate and nitrite supplementation of the calves by feeds and water could be stated. Imitation of possible field conditions when mainly water, but feeds too, may contain higher nitrate and nitrite levels, was carried out by peroral administration of an aquaeous solution of KNO3 to calves. The administered dose was increased from one to 2, 5 and 10 g per animal and day, respectively, in weekly intervals. MtHb determination in the blood of experimental calves on day 1 and 5 of the administration of 1 g KNO3 revealed no significant values. On day 1 and 5 of the administration of 2, 5 and 10 g KNO3 per animal and day, respectively, a significant increase of MtHb levels in the blood of calves was observed 2 and 3 hours after administration, followed by a decrease 4 hours after administration. The maximum values of MtHb in the blood of experimental calves, observed 3 hours following application of the respective KNO3 dose, were within the tolerance limits of the reference values. In urine, 3 hours after the administration of 10 g of KNO3 a mean nitrate value of 941.40.

Age Factors