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J Pospísil

Publications and source records attributed to J Pospísil.

At least 73 records · Page 4Linked to original sources
PubMed1984

Basic haematological values in antelopes--II. The Hippotraginae and the Tragelaphinae.

Basic haematological values in 49 animals of five species of the subfamily Hippotraginae, namely the roan antelope Hippotragus equinus, sable antelope Hippotragus niger, adax antelope Addax nasomaculatus, gemsbok oryx Oryx gazella gazella and scimitar horned oryx Oryx damah and in 51 individuals of five species in the subfamily Tragelaphinae, including the bushbuck Tragelaphus scriptus, nyala Tragelaphus angasi, greater kudu Tragelaphus strepsiceros, cape eland Tautotragus oryx and bongo Bocercus euryceros are reported. The erythrocyte counts were in the range of 12.62 X 10(12)/l in the gemsbok oryx to 6.44 X 10(12)/l in the bongo, the haematocrit values varied from 0.488 in the nyala to 0.380 in the roan antelope and for the haemoglobin highest levels (164.0 g/l) were noted in the adax antelope, and the lowest (105.5 g/l) in the bongo. Leukocyte counts were found mostly in the normal human range and varied from 7.17 X 10(9)/l in the adax antelope to 4.05 X 10(9)/l in the nyala, only in the greater kudu decreased values of 3.02 X 10(9) were estimated. These results are compared with findings taken from the literature, and with the normal human range.

Animals↗
PubMed1984

Basic haematological values in antelopes--III. The Reduncinae and the Antelopinae.

Basic haematological values were measured in 50 individuals of five species falling under the subfamily Reduncinae, including the mountain reedbuck (Reduncula fulvorufula), the eastern waterback (Kobus ellipsiprymnus ellipsiprymnus), the defassa waterbuck (Kobus ellipsipyrmnus defassa), the lechwe waterbuck (Kobus leche) and the Lady Gray's waterbuck (Kobus megaceros) and in 45 animals of three species of the subfamily Antelopinae, including the springbok (Antidorcas marsupialis), the Grant's gazelle (Gazella Granti) and the dama gazelle (gazella dama). The highest mean erythrocyte counts were found in the male springbok: 11.72 X 10(12)/l, the lowest in the lechwe waterbuck: 8.39 X 10(12)/l, the mean haematocrit values varied from 0.538 in the lechwe waterbuck to 0.443 in the defassa waterbuck and the mean haemoglobin content ranged from 181.2 g/l in the male springok to 151.8 g/l in the defassa waterbuck. Leukocyte counts were mostly shown to be in the human range, in the subfamily Reduncinae at the lower limit; only in the mountain reedbuck decreased values of about 3.5 X 10(9)/l were demonstrated. These results are compared with information from the literature and with the normal human range.

Animals↗
PubMed1984

Basic haematological values in antelopes--IV. A comparison and concluding remarks.

Comparison of mean erythrocyte counts, mean haematocrit values, mean haemoglobin content and mean corpuscular volume of the red cell is presented for 21 species of antelopes (four species being excluded because of the small number of animals investigated). A direct relationship of haematocrit values and haemoglobin content and an inverse relationship of red cell counts and mean corpuscular volume of the erythrocytes were noted. The significance of an increased total surface area for oxygen exchange is discussed and values obtained in the red blood picture are compared with those of domesticated animals (cattle, goat and sheep) taken from the literature. Mean leukocyte counts were found to be in the human range with the exception of two species, but significantly lower than in domesticated artiodactylids. Problems in assessing the general health, the age, the effect of diet and of environment in captivity are discussed. Problems of methodology, especially of blood sampling, are given comparing results in manually restrained and in sedated animals.

Animals↗
PubMed1983

[The physiological inhibitors of blood coagulation. 1. Antithrombin III (AT III)].

In a brief survey, recent data on the molecular structure and functions of antithrombin III as well as on the similarity of identity with antithrombin III of newborns and mammals are referred to. Moreover, the survival time in circulation and its broad inhibiting spectrum comprising not only all activating factors of coagulation, but also other proteases, is discussed. The accelerating effect of heparin on response and possible mechanisms of this acceleration are discussed. The various procedures of determination are briefly dealt with. Furthermore, the distinct tendency towards thromboembolic complications occurring in patients with only a slight reduction of antithrombin III level is dealt with, as it was described in inherited and acquired deficiency of antithrombin III. Finally, the possibilities of therapy for this deficiency are discussed and is underlined on the key position of antithrombin III for maintaining the balance of coagulation.

Antithrombin III↗
PubMed1983

Changes of the activity of acid phosphatase and beta-glucuronidase in isolated platelets of whole-body irradiated rats.

In the work presented here we paid our attention to studying changes of the activity of two lysosomal enzymes-acid phosphatase and beta-glucuronidase in platelets after whole-body irradiation and application of certain clinically applied antifibrinolytics (Antilysin Spofa and epsilon-aminocaproic acid) on the activity of these enzymes in isolated platelets. From the results it is obvious that the activity of acid phosphatase and beta-glucuronidase increases in platelets of irradiated rats with a maximum on the 11th day after irradiation. In the same time interval after irradiation the most remarkable thrombocytopenia was observed. The application of Antilysin or EACA to intact, non-irradiated rats affects remarkably neither the activity of the followed enzymes nor the count of platelets. A statistically significant thrombocytopenia, in a comparison with controls was found in whole-body irradiated rats who received EACA or Antilysin. The postirradiation increase of the level of acid phosphatase in platelets exerts a similar character in rats who received EACA or Antilysin as in those who were only irradiated with a difference that the increase of the level of this enzyme was essentially lower in all the time intervals of interest. The beta-glucuronidase level in platelets of rats, who received EACA, was essentially unchanged as compared to controls. The application of Antilysin altered remarkably the level of beta-glucuronidase in platelets of whole-body irradiated rats in a comparison with a level of this enzyme in platelets of rats who received no Antilysin. Most remarkable changes were observed in latter time intervals (11th and 15th day) when the beta-glucuronidase level in platelets of rats after the application of Antilysin was remarkably higher than that in solely irradiated rats.

Acid Phosphatase↗
PubMed1983

[Physiologic inhibitors of blood coagulation. 2. Alpha 2-macroglobulin, alpha-antitrypsin and the C1 inhibitor of complement].

Three physiological inhibitors of blood coagulation - alpha-2-macroglobulin, alpha-1-antitrypsin, and C-1-inhibitor of complement - are dealt with in a brief survey. The point is that these are proteins of the organism with a defence character which are also able to inhibit an extraordinarily broad spectrum of proteases. Some recent findings about their molecular structure, manner of response, and inhibitory spectrum are represented. Comparisons are made to corresponding proteins in mammals, in alpha-2-macroglobulin and even in lower vertebrates. Moreover, the inherited deficiency of these three inhibitors are represented with respect to human diseases and changes of their blood level in the course of various diseases are referred to.

Animals↗
PubMed1983

[Changes in various blood platelet function tests in rabbits exposed to whole-body irradiation].

With a selected spectrum of coagulation tests the functioning capacity of thrombocytes was investigated in rabbits exposed to a whole body irradiation by means of 60Co radiation with a LD 5/30. A reduced retraction could be proved for times of irradiation (the 5th, 8th, 11th, 21st, 35th, and 56th day). A reduced formation of malondialdehyde could be identified in thrombocytes on the 8th and 21st day after irradiation. No changes could be found in determining adhesiveness, platelet aggregation caused by ADP, and PF3A and PF3F tests. In the course of additional investigations (coagulation time in unprepared and siliconized glass tubes, thromboelastogramme, activated partial chromboplastine time), significant changes of coagulation time could be observed in siliconized glass tubes on the 8th, 11th, 21st, and 56th day following irradiation.

Animals↗
PubMed1983

[Flavellagic acid influence on blood coagulation and hemostasis disturbed by whole body irradiation].

By experimentations in vitro with human blood, we found out that an addition of flavellagic acid influences the initial stage of the coagulation system by activating the XIIth coagulation factor. So there is another substance besides the ellagic acid that activates in solution the XIIth coagulation factor. Our experimentations on sound rats showed that an intravenous administration of flavellagic acid in a dose of 0.7 mg/kg body weight has a short-term hemostatic action and that the r and k values and the m epsilon value in the thrombelastogram are increased. There was a similar effect in rats receiving an intravenous injection of flavellagic acid on the twelfth day after a whole-body irradiation with 8.0 Gy.

Animals↗