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Biomedical subjects

J Pradère

Publications and source records attributed to J Pradère.

5 recordsLinked to original sources
PubMed1986

[Blood viscosity in osteonecrosis of the femur head].

The viscosity of total venous blood was studied in 21 patients with osteonecrosis (ON) of the femoral head, and compared with the viscosity of 43 control patients, blood donors of the same mean age, and with the viscosity of 17 patients suffering from hip arthrosis. Measurements were carried out on a rotary resistance meter with coaxial cylinders. Along with the viscosity, certain biological, hematological and biochemical parameters, making up the main macro-rheological parameters, were measured in the same blood samples. Statistical analysis of the results confirms the hyperviscosity of total venous blood in patients with ON of the femoral head. This hyperviscosity does not seem correlated with the biological parameters studied, contrary to the viscosity of the blood in the control group. It is likely secondary to other factors, intrinsic to ON, and especially microrheological factors.

Adult↗
PubMed1982

[Blood biorheology and ischemic cerebrovascular accidents].

Blood hyperviscosity is usually observed in ischemic stroke. Our purpose was to study relations between viscosity and the different parameters of blood that influence viscosity, and to search abnormalities of circadian rhythms. 18 stroke patients (8 females and 10 males mean 65.4 years) and 12 normal subjects (4 females and 8 males, mean 68 years) were studied. The measures were realised within the 48 hours after stroke at 6 p.m. and 12 p.m. and the fourth day at 6 p.m. and 12 p.m., by means of a Taylor-Couette type rheometer. Stroke patients have a significant increase of their blood viscosity, but without elevation of blood hematocrit or fibrinogen within 48 hours. Stroke patients have no nocturnal decrease of viscosity, and they don't present the normal circadian periodicity. Perhaps would this phenomenon explain the diurnal variations in occurrence of strokes?

Adult↗
PubMed1979

[Local osseous blood flow measured with radioactive microspheres: correlations with intra-medullary pressures].

The authors studied in the dog, using radioactive microspheres, the blood bone outputs of the trochanter, the femoral diaphysis and the tibial diaphysis, and measured, in a simultaneous fashion, the intra-medullar pressures in these bone regions. A same hierarchy of outputs is consistently found in all animals : the trochentarian outputs are always the highest, and next come, in decreasing order, the outputs of the femoral diaphyses and the tibias. On the other hand, the intra-medullar pressures, although differing according to the bone regions, always have rather superposable rates, so that the neighboring intra-medullar pressures always correspond to radically different outputs. It is thereby demonstrated that the intra-medullar pressures, as an isolated parameter, cannot accurately reflect the rate of bone output.

Animals↗
PubMed1975

[Rheumatoid synovial fluid].

In making a comparative study of different parameters in the examination of synovial fluid (rheumatoid factors, ragocytes, leucocytes, synovial complement, immunoglobulins) the authors show that rheumatoid fluid has characteristics that make differentiation from other inflammatory arthropathies possible on a statistical basis, thanks to the test for the homogeneity of the means. The presence of these characteristics seems to constitute a diagnostic argument which can be measured by mathematical methods.

Arthritis↗