PubMed Health⌕ Search

Biomedical subjects

J Proulx

Publications and source records attributed to J Proulx.

12 recordsLinked to original sources
PubMed1992

Influence of an agonist of gonadotropin-releasing hormone (buserelin) on estrus synchronization and fertility in beef cows.

The objective of this experiment was to determine the effect of sequential treatment with buserelin (a GnRH agonist) and cloprostenol (a prostaglandin F2 alpha analog) on estrous response and fertility in beef cattle with different ovarian conditions. On d 0 (1st d of treatment), the control group (n = 52, 10 heifers and 42 cows) and the GnRH group (n = 48, 10 heifers and 38 cows) received 2 mL of saline or 2 mL of Receptal (8 micrograms of buserelin), respectively. On d 6, all cows that had not exhibited spontaneous estrus were given i.m. 500 micrograms of cloprostenol (PGF). Ultrasonography on d 0 and assays of progesterone in blood on d -11, 0, and 6 were used to identify follicular and luteal status of animals. Cattle were observed for estrus from d 0 to 10. Cows showing estrus were bred artificially 12 h after onset of estrus. Over the 10-d period, the number of cows detected in estrus and pregnancy and conception rates were identical for the two groups. However, between d 0 and 6, the proportion of cows exhibiting estrus was lower (P less than .01) in the GnRH group than in the control group. Between d 6 and 10, the synchronization rate and precision of estrus were greater (P less than .01) in the buserelin-treated group than in the control group. Conception rate and interval from PGF injection to onset of estrus were not different between the two treatment groups. Presence of a large (greater than 10 mm) follicle on d 0 enhanced synchronization rate and precision of estrus.(ABSTRACT TRUNCATED AT 250 WORDS)

Animals↗
PubMed1990

Validation of a non-invasive device to measure intracavernous pressure as an index of penile rigidity.

Many authors agree with the importance of developing devices to measure penile rigidity. The devices that have been developed over recent years have defined penile rigidity in terms of stiffness. Penile stiffness, however, is believed to result from an increase in intracavernous pressure. The device presented here was therefore designed to estimate intracavernous pressure, rather than penile stiffness, as an index of penile rigidity. Validation of the penile cuff device was achieved by simultaneously recording penile cuff pressure and intracavernous pressure on patients undergoing artificial erections. The results showed a linear relationship and highly positive correlation coefficients between the 2 measures. The results demonstrate that the penile cuff may be used to estimate intracavernous pressure as an index of penile rigidity. The findings are discussed in terms of the possible applications of the cuff as a clinical tool to measure both penile tumescence and penile rigidity.

Adult↗
PubMed1990

Effect of vitamin E and selenium supplementation on some immune parameters following vaccination against brucellosis in cattle.

Twenty-four 7-mo-old beef heifers (Charolais Simmental cross), weighing 213 kg, were used to determine the effect of vitamin E (VitE) and(or) selenium (Se) supplementation on the humoral response to a standard dose of Brucella abortus strain 19 vaccine and on the levels of naturally occurring immunoglobulins (Ig) to several antigens. The treatments were as follows: Group 1, no supplement; Group 2, supplementation with 6 g of elemental Se; Group 3, supplementation with 1,400 IU/d of VitE; and Group 4, Se and VitE supplements combined. There were no significant differences in anti-B. abortus IgG1, IgG2, or IgM antibody levels due to Se, VitE or Se/VitE treatments; the concentrations of IgA antibody were too low to be measured with the ELISA test used. Statistical analysis revealed that the levels of total and IgM natural antibody to Salmonella typhimurium were higher in Group 3. Perhaps VitE supplementation given in conjunction with B. abortus vaccine enhanced the production of antibody to S. typhimurium in several animals whose humoral system had been activated by previous exposure to this organism.

Animals↗
PubMed1990

Identification of HIV-1 vpr product and function.

To investigate the role of vpr (viral protein R) in the replication and cytopathicity of human immunodeficiency virus type 1 (HIV-1), infectious proviruses were constructed that were isogenic except for the ability to produce the protein product of vpr. The experiments described here demonstrate that vpr encodes a 96 amino acid 15 kDa protein. The vpr product increases the rate of replication and accelerates the cytopathic effect of the virus in T cells. Vpr acts in trans to increase levels of viral protein expression. The stimulatory effect of vpr is observed to act on the HIV-1 LTR as well as on several heterologous promoters.

Cytopathogenic Effect, Viral↗
PubMed1989

The differentiation of francophone rapists and non-rapists using penile circumferential measures.

Since 1977 there have been seven published and two unpublished reports concerning the differentiation of rapists and non-rapists using penile circumferential measures. Of the published experiments, six report significant differences between groups. The purpose of the present investigation was to extend the scope of this work using a French-speaking population. Ten rapists and ten non-rapists were exposed to four classes of audiotaped stimuli: mutually consenting, rape, aggressive and sexually neutral episodes. Penile circumference changes were recorded during stimulus presentation. The results indicated that while rapist and non-rapist groups were not distinguished in terms to their response to mutually consenting sex, the two groups were distinguished with respect to their responses to rape episodes. The discrimination was even more marked when the results were individually analyzed using the rape index. Thus we were able to validate, in French-speaking subjects, the differentiation between rapists and non-rapists using penile measures. Several hypotheses are advanced which could explain the differences between experiments which demonstrate and those which fail to demonstrate discrimination between groups.

Adult↗
PubMed1979

[Early and late outcome after aortocoronary bypass: experience in 500 cases].

Between 1971 and 1976, 500 patients underwent aortocoronary bypass surgery. There were 15 operative deaths (3%) and the total frequency of perioperative infarction was 7%. The operative mortality was 7.4% in unstable angina, as compared with 1.1% in stable angina (P less than 0.01). The proportion of grafts patent at 2 weeks was 92% and at 18 months 87.6%. Postoperative follow-up was complete for 99% of the patients. There were 15 late deaths (3%) and the rates of survival at 2 and 4 years were 94.4% and 92.1% respectively. The actuarial curve of survival after surgery was not significantly different from that of the general population. After a mean follow-up of 27 months 73% of the patients were completely free of angina and 19% were markedly improved. The rate of recurrence of angina averaged 10% per year and the annual infarction rate was 0.7%. Fourteen patients (3%) underwent reoperation during the follow-up period. Thus, coronary revascularization surgery offers effective and sustained relief of incapacitating angina and might also improve survival if the operative mortality is low.

Adult↗
PubMed1979

You are what you wear.

Uniforms and professional roles are frequently tied in the minds of both staff and patient, so it may be advisable to return to greater use of uniforms by hospital professional staffs.

Attitude of Health Personnel↗