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Biomedical subjects

J Prucha

Publications and source records attributed to J Prucha.

6 recordsLinked to original sources

[Polychlorinated biphenyls (PCB) in human adipose tissue].

This study describes the contamination of human adipose tissue with six selected polychlorinated biphenyls (PCB) known as "indicator congeners", with PCB no. 49 and the mixed inducer PCB nos. 156, 170, and 189. The low chlorinated biphenyls nos. 28, 49, and 52 could not be found in the tissue samples, while the average concentration of PCB no. 101 was 9.0 micrograms/kg. The content of PCB nos. 138, 153, and 180 was slightly below the values published by the "Deutsche Forschungsgemeinschaft" (DFG). The mixed inducer nos. 138, 156, 170, and 180 amounted to approximately 40% of all the PCBs measured. The PCB contamination was positively correlated with age: for the age group 61-70 years, with the exception of PCB no. 101, a distinct increase in the concentrations could be observed.

Adipose Tissue↗

[Pollution of indoor air in large-scale kitchens and laundries by volatile halogenated hydrocarbons].

The study demonstrates that the agents used for dishwashing and in the central laundry are already slightly contamined with halogenated hydrocarbons and formaldehyde. Analyses of the washing lyes yield considerably higher concentrations of halogenated hydrocarbons. Especially in the dishwater a relatively high concentration of trichloromethane (chloroform) was detected. Obviously these halogenated hydrocarbons are also present in relatively high concentrations in the air of the corresponding working places. However, the concentrations of individual halogenated hydrocarbons and formaldehyde are clearly below the respective threshold limit values.

Air Pollutants, Occupational↗

[Environmental characterization: air pollution].

During the years of the epidemiological group-diagnostic examination (1982-1986) it was attempted to characterize the atmospheric air pollution in the industrial Rhine-Main area (Wiesbaden and Frankfurt) and, in comparison, in two control areas (Freiburg with the adjacent High Black Forest and the Starnberg area). For this the measurements of the air measuring stations of the network for emissions of the German Umweltbundesamt (Federal Environmental Protection Agency) at Berlin and Frankfurt were used and well as those of the Hessische Landesanstalt für Umwelt, Wiesbaden (Hessian Office for Environmental Protection); Landesanstalt für Umweltschutz Baden-Württemberg, Karlsruhe (Regional Office for Environmental Protection of Baden-Württemberg); Bayerische Landesanstalt für Umweltschutz (Bavarian Office for Environmental Protection, Munich), were used. The comparison of the different measuring components used shows the pollutant concentration in the air at the measuring stations in Wiesbaden and Frankfurt attains the highest values. Opposed to that, the pollutant concentration in the areas Freiburg with the adjacent Black Forest and in the region of Starnberg can be judged to be relatively low. No statement can, unfortunately, be made on the heavy metal burden in the air of the Starnberg area, since heavy metal in the air have not been analysed.

Air Pollution↗

[Environmental characterization: weather and climate].

In order to characterize the weather and the climate in the area of industrial Rhine-Main area (Wiesbaden and Frankfurt) and in the two control areas (Freiburg with the bordering higher region of the Black Forest and the Starnberg area), relevant measuring data was provided by the German Meteorological Service, Centre of the Medicometeorological Research Establishment, Freiburg. The monthly as well as yearly climatic values of the years 1982-1985 were employed for the following stations: Frankfurt Airport; Wiesbaden South; Freiburg Meteorological Office; Munich Airport Riem which are representative for our areas under examination. For the characterization of the climate in the study areas the following parameters were used: temperature degrees C; relative humidity of the air in %; amount of rainfall in mm; duration of sunshine; wind distribution. The climatic values were interpreted for the years 1982-1985 of the epidemiological group-diagnostic examination of children.

Climate↗

[Heavy metal content of the children's hair].

In the framework of the epidemiological group-diagnostic studies in the industrial areas Rhine-Main (Wiesbaden and Frankfurt) with a relatively high air pollution as well as in two control areas (Freiburg and Starnberg) with lower air pollution, hair samples from more than 2500 ten-year-old children were taken. After an appropriate washing process (removal of the exogenic load) and wet incineration, the hair samples were examined by AAS- for their heavy metal content (Cd, Pb, Fe and Zn). The evaluation of the results over the time of the examination from 1982 until 1986 shows that the hair samples from children in the burdened area Rhine-Main with high air pollution have higher lead as well as cadmium values than those of the control area Freiburg with the bordering region of the Black Forest. Furthermore it can be clearly recognized in the five years of the examination of children's hair that the contamination or the content of toxic heavy metals such as Cd and Pb in the polluted region of Wiesbaden is distinctly decreasing over the years. Surprisingly, increased zinc, cadmium and also, during the last two years, increased lead values in children's hair were detected in the Starnberg area. During the five years of examination there was a correlation between the heavy metal content in children's hair and the heavy metal content in airborne dust of the burdened area; this is particularly true for cadmium.

Air Pollution↗