Colliding Black Holes: How Far Can the Close Approximation Go?
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Biomedical subjects
Publications and source records attributed to J Pullin.
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The problem of dropout rates in outpatient relapse prevention groups for "problem" drinkers is addressed. To test the hypothesis that the dropout rates were due to anxiety and lack of clarity among the participants about the purpose and expectations of the group, a structured induction was developed. The results obtained show that the induction made a significant difference in reducing the dropout rate. These findings can also be applied to other outpatient groups.
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1. A 3-hr period of complete autonomic blockade was induced in anaesthetized sheep and dogs using a continuous intravenous infusion of trimetaphan camphorsulphonate and atropine. Circulatory, respiratory and metabolic parameters were studied over 24 hr or until the animal died, whichever came first.2. After termination of the blockade all animals remained hypotensive and within a few hours all died in irreversible shock which was not accompanied by any of the otherwise characteristic respiratory or metabolic consequences of circulatory failure.3. Administration of trimetaphan alone for a similar period was innocuous.4. When during complete autonomic blockade a continuous infusion of dopamine or hypertensin was additionally administered mortality rate was halved but all survivors remained hypotensive.