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Biomedical subjects

J Q Xu

Publications and source records attributed to J Q Xu.

29 records · Page 2Linked to original sources

[Replantation of frozen and boiled autogenous mandible].

Mandibles devitalized by freezing or boiling after being removed from animals were reimplanted to evaluate their potentials of reunion and growth with X-ray and histological methods. The results suggested that the osteo-induction may play a partial role in the bone healing of frozen bone graft besides "creeping substitution", while the boiled one only provided a scaffold into and around which bone formation can occur. According to the rate and degree of bone graft repair, the frozen was better than the boiled which was resorbed and replaced at a slower rate.

Animals↗

Comparative cross-over pharmacokinetic study on two types of postcoital contraceptive tablets containing levonorgestrel.

A pharmaceutical and pharmacokinetic study was carried out on levonorgestrel tablets from two different sources (Hungarian- and Chinese-made). Both preparations contained 0.75 mg levonorgestrel and had been shown to have similar contraceptive efficacy and side effects when used for postcoital contraception. Absorption and bioavailability of the Hungarian-made tablets were greater as evidenced by higher serum concentrations of levonorgestrel, a greater area under the concentration-time curve during the first 24 hours, and a more marked suppressive effect on SHBG levels. These differences most probably reflect differences in their pharmaceutical formulation, in particular the extent of tablet dissolution and the degree of micronisation of levonorgestrel.

Absorption↗