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Biomedical subjects

J R Allison

Publications and source records attributed to J R Allison.

At least 19 recordsLinked to original sources

On assessing the benefits of public mosquito control practices.

Public mosquito control can be characterized as a nonmarket good whereby the absence of price-quantity information normally used to determine demand and benefits creates a dilemma to the researcher. In response to this dilemma economists have advanced several methods to assess demand components and value of nonmarket goods. The contingent market valuation (CMV) approach is but one method. This paper outlines the relevant theory behind benefit measures, and develops and demonstrates a CMV approach that can be used to value public mosquito control.

Animals

A comparison of alternative mosquito abatement methods using benefit-cost analysis.

Benefit-cost analysis can be used to evaluate and compare projects that involve alternative mosquito control methods. A comparison of two such projects in Chatham County, GA indicated that source reduction was a contributing factor in the reduction of ground adulticide applications and quantities, and annual female densities per light-trap night of the predominant saltmarsh mosquito species in the area. Net benefits realized from source reduction were $591,319 as opposed to $409,823 and discounted net benefits were $377,729 versus $284,511 (source reduction project vs. chemical control project) demonstrating the relative effectiveness of the source reduction project in our application. Because of unique differences between areas and projects, generalizations of the above conclusion are cautioned, although the approach is easily adapted.

Cost-Benefit Analysis

Scintigraphic diagnosis of hepatic hemangioma: its role in the management of hepatic mass lesions.

Hepatic cavernous hemangiomas are benign tumors of the liver that are often an incidental finding. They are usually asymptomatic but may cause symptoms when traumatized, may bleed spontaneously, or may produce pain by virtue of their large size and mass effect. A retrospective analysis of the clinical presentation, liver function tests, and diagnostic imaging procedures in 20 patients with hepatic hemangiomas is presented and the literature is reviewed. The 20 patients had 27 mass lesions as seen on liver scintigraphy, computed tomography, or sonography. Technetium-99m-labeled red blood cell flow studies and blood pool scintigrams showed delayed filling of the mass lesions, diagnostic of hemangiomas. This finding was not encountered in any other type of lesion. A new diagnostic algorithm is proposed in which blood-flow and blood-pool scintigraphy play a more prominent role in the diagnostic workup. According to this algorithm, if liver function tests in a patient with hepatic mass are either normal or abnormal and suggestive of hepatocellular dysfunction, the patient should undergo hepatic blood-flow and blood-pool studies.

Adult

The use of present value criterion applications in making mosquito control decisions.

Present value criterion in mosquito-control decisions was presented with several examples that illustrate its applicability and the modifications it allows. An actual case study from data derived in Chatham County, GA was presented. Findings of this case study suggest that permanent control contributed to the reduction of ground adulticide applications and quantities, adult densities of female mosquitoes per light-trap night, and the proportion of primary target salt-marsh species relative to total species per light-trap night.

Animals

Radiation-induced basal-cell carcinoma.

Four patients developed 129 basal-cell carcinoma (BCC) in areas of prior radiation without evidence of radiation damage. The time lag between radiation and appearance of the cancers was 20 years. It is proposed that we are dealing with a subset of the population not previously recognized. These patients were not related to other groups, such as the nevoid basal-cell carcinoma syndrome.

Aged

Treatment of immature and mature Fasciola hepatica infections in sheep with triclabendazole.

A new benzimidazole anthelmintic, triclabendazole (CGA-89317) was found to be highly efficient against mature and early immature Fasciola hepatica infections in sheep. At the dose rate of 2.5 mg/kg the efficiency was 90 and 98 per cent against flukes aged eight and 12 weeks respectively. At 5 mg/kg the drug was 92 and 98 per cent efficient against flukes aged four and eight weeks respectively and 100 per cent against 12-week-old flukes. An efficiency of 93 and 98 per cent was achieved against one-week-old flukes and 99 to 100 per cent against flukes aged two to four weeks at 10 mg/kg. At this dose rate the drug had 100 per cent efficiency against six-week-old flukes. If the dose was increased to 15 mg/kg, 98 per cent efficiency was achieved one day after infection. Triclabendazole was equally efficient when administered orally or by intraruminal or intra-abomasal injection. The maximum tolerated dose of 200 mg/kg was established.

Animals

Ga-67 scan as a prognostic indicator in primary lung carcinoma.

GA-67 scintigraphy was performed on 74 patients with a variety of histologic types of untreated primary lung carcinoma. Ga-67 uptake was determined, allowing for differences in tumor size. Ga-67 uptake was compared with the response to the incidence of metastases, and to host survival in the 74 patients. From these results, it is suggested that the greater the Ga-67 accumulation in the tumor, the higher the incidence of metastases and the shorter the host survival. Ga-67 scintigraphy appears to be a valuable tool in indicating the prognosis following radiation therapy in patients with primary lung carcinoma.

Adenocarcinoma

The relationships between the Ga-67 uptake and nuclear DNA Feulgen content in thyroid tumors: concise communication.

It has been reported that Ga-67 uptake by malignant tumors differs somewhat according to the histologic type. Previously, we reported that uptake of Ga-67 is predictably low in well-differentiated adenocarcinoma of the thyroid gland but high in anaplastic carcinoma and malignant lymphoma. We studied the relationship between Ga-67 uptake and nuclear DNA content in four papillary adenocarcinomas, three follicular adenocarcinomas, three anaplastic carcinomas, and five malignant lymphomas of the thyroid gland. In anaplastic carcinoma and malignant lymphoma, the nuclear DNA content and proliferative index were significantly higher than in well-differentiated adenocarcinoma. These results suggest that there is close correlation between Ga-67 uptake and degree of malignancy of thyroid tumor cells.

Adenocarcinoma

Radiation dermatitis: a case report.

A unique form of vasculitis occurring six months after radiation therapy for postoperative breast cancer is described herein. This rare, unexplainable reaction is a very unusual occurrence.

Aged

Knuckle pads.

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Adult