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Biomedical subjects

J R Babcock

Publications and source records attributed to J R Babcock.

12 recordsLinked to original sources
PubMed2001

Indium-cadmium-oxide films having exceptional electrical conductivity and optical transparency: clues for optimizing transparent conductors.

Materials with high electrical conductivity and optical transparency are needed for future flat panel display, solar energy, and other opto-electronic technologies. In(x)Cd(1-x)O films having a simple cubic microstructure have been grown on amorphous glass substrates by a straightforward chemical vapor deposition process. The x = 0.05 film conductivity of 17,000 S/cm, carrier mobility of 70 cm2/Vs, and visible region optical transparency window considerably exceed the corresponding parameters for commercial indium-tin oxide. Ab initio electronic structure calculations reveal small conduction electron effective masses, a dramatic shift of the CdO band gap with doping, and a conduction band hybridization gap caused by extensive Cd 5s + In 5s mixing.

Journal Article↗
PubMed1979

Morbidity of pelvic lymphadenectomy.

A retrospective review of 100 patients undergoing pelvic lymphadenectomy alone or with additional surgery was done to assess the morbidity and to help identify factors contributing to a high wound morbidity. Major wound morbidity occurred in 8 per cent of patients, while 16 per cent had minor wound problems. Factors contributing to wound morbidity included urinary tract infection, altered metabolic states, and the use of wound drains. Other morbid events are tabulated.

Drainage↗
PubMed1979

Ultrasound-guided percutaneous nephrostomy in the pediatric patient.

Percutaneous nephrostomy drainage may be established rapidly using ultrasonic guidance in severely ill pediatric patients with obstructive uropathy. B-mode ultrasonography has proved to be rapid, accurate and free of irradiation hazards, making it applicable to children with little or no sedation.

Adult↗
PubMed1978

Progression of the immune response to solubilized tumor antigens.

Local adoptive transfer assays (LATA) were used to analyze and compare the progression of the immune response in C3H/HeJ mice to irradiated tumor cell vaccine and to crude 3M KCl solubilized antigens extracted from a syngeneic methylcholanthrene-induced fibrosarcoma. Sequential LATA performed 2, 6, 9, 12 and 15 days after soluble antigen pretreatment of spleen cell donors revealed a sinusoidal evolution of lymphoid cell activity. An initial brief period of potent tumor facilitation (days 6-9) was followed by a phase of tumor neutralization (days 9-12) which decayed by day 15. On the other hand, spleen cells from donors sensitized with irradiated tumor cells exhibited consistent tumor neutralization which was sustained throughout 15 days. Thus the tumor growth facilitation observed only in CSA-treated donors may represent a qualitative difference in the immune state induced by soluble, as opposed to cellular, forms of tumor antigen.

Animals↗
PubMed1977

Morbidity and mortality of renal exploration for cyst.

Surgical exploration for a renal mass is a procedure associated with a low mortality and morbidity, even in a population with a median age of 58 years, most of whom were listed according to the American Society of Anesthesiologists as class II or greater. As a consequence, the procedure warrants serious consideration as a diagnostic measure. Nonsurgical diagnostic procedures are associated with less immediate risk to the patient but with less immediate risk to the patient but with more limited accuracy. The decision as to which methods of evaluation to use in each particular patient must be individualized. The general and related symptoms, physical and laboratory findings and the quality and results of roentgenography and puncture studies of the patient warrant consideration in recommending a reasonable course. Whatever procedures are recommended, the patient should be adequately informed to recognize that alternative treatment approaches are available.

Chicago↗
PubMed1976

Renal changes after an uncomplicated antireflux operation.

Persistent defects were noted after successful ureteral reimplantations in 91 per cent of patients with preoperative pyelographic changes. The renal ratio between the kidney with reflux and its contralateral normal mate also was found to be static despite the eradication of infection. It is hypothesized that a degree of renal dysgenesis is not uncommon in association with reflux and may be the major factor in explaining these findings.

Atrophy↗
PubMed1973

Adrenal corticosteroid-induced renal cystic disease in the newborn hamster.

A new model of renal cystic disease was developed in newborn Syrian hamsters by the repeated injection of 9-fluoroprednisolone acetate (9-FPA), a long-acting adrenal corticosteroid. Kidneys harvested from the tenth to the fourteenth day of age showed diffuse cystic dilatation of nearly all cortical convoluted tubules. Microdissection revealed that cystic changes primarily involved proximal convoluted tubules and, to a lesser degree, the distal tubules. Electron microscopy showed immaturity of development and varying degrees of degeneration of the cells of the proximal convoluted tubule. Intraluminal obstruction was not detected and therefore could not account for the cystic changes. Analysis of electrolytes in serum and selected tissues showed a significant reduction in potassium and sodium of serum, and significant depletion of potassium, magnesium and calcium in the skeletal muscle. Thus, there was no direct relationship between an electrolyte deficiency and the cystic changes.

Animals↗