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J R Blanco

Publications and source records attributed to J R Blanco.

At least 37 records · Page 2Linked to original sources
PubMed2001

[Determination of antibodies against A-60 antigen for diagnosis of M. tuberculosis infection. A useful tool for rationalization of chemoprophylaxis in HIV patients].

OBJECTIVE: To identify M. tuberculosis infection in HIV patients by use of PPD and an ELISA test detecting the presence of antibodies against antigen A-60 of M. bovis. METHODS: 116 incoming HIV patients were classified according to the CDC. The status of M. tuberculosis infection was probed with PPD (RT-23) and the state of anergy was estimated by a Multitest CM1 (Multitext). The presence of circulating antibodies of the IgG class against antigen A-60 was analysed by an ELISA. The clinical course of the patients was followed for 24 month. RESULTS: A positive serology (A-60) was found in 52.58% of the patients, coinciding with 70.45% of the positive PPD (p < 0.003). This statical observation was found when we studied all of the individuals, and those with more than 500 CD4 lymphocytes. The Multitext was positive in 11.11% of the patients with PPD (-), all of them without antibodies against A-60. However, 42.2% of the patients who were PPD and Multitext (-), had circulating antibodies against A-60. The following up of the patients during 24 months allowed the detection of 7 news cases of pulmonary tuberculosis, 4 of them had a positive A-60 serology, and 4 were anergy. CONCLUSIONS: HIV patients with M. tuberculosis infection have circulating antibodies against A-60 antigen of M. bovis with independence of their immunity status. In anergic patients the presence of this antibodies can be an useful tool for rationalizing the prophylaxis against M. tuberculosis. A seropositivity (A-60) indicates as well as does PPD a previous contact with M. tuberculosis.

AIDS-Related Opportunistic Infections↗
PubMed2000

Incidence of pericardial effusion in pulmonary tuberculosis.

Tuberculosis (TB) is one cause of pericardial disease. In order to know the incidence of tuberculous pericardial effusion (TPE) in patients with pulmonary tuberculosis (PT), the factors associated with their presence and whether human immunodeficiency virus (HIV) patients have a higher risk, we analyzed different parameters and performed an echocardiography to evaluate the presence of TPE. The incidence of TPE was 14.1%, and the presence of pleural effusion was associated with TPE (OR 24.39). HIV patients do not have a higher risk of TPE, independently of immunosuppression. It is necessary to eliminate the presence of TPE in patients with PT, mainly in those with pleural effusion.

Adult↗
PubMed1999

[Seroepidemiology of Bartonella henselae infection in HIV-infected patients].

BACKGROUND: Bartonella henselae infections are closely related to numerous clinical infections of growing interest in Spain. Since immunosuppressed patients are a potential risk group for infection by this bacteria, the aim of the present was to study the seroepidemiology of B. henselae infection in a risk group (patients with HIV infection) and in a control group (donors). PATIENTS AND METHODS: In October, 1997, antibodies versus B. henselae were determined at different dilutions (cut off > or = 1:64) by immunofluorescence in 52 patients with HIV infection and 85 donors. An epidemiologic study included age, sex, smoking, alcohol intake, INVDA, HIV infection, AIDS stage, cutaneous anergy, CD4 lymphocyte count, antiretroviral treatment and chemoprophylaxis versus P. carinii. RESULTS: Nine of the patients with HIV infection (17.3%) and five donors (5.88%) presented titers > or = 1:64 with no significant differences (p = 0.06) (adjusted OR: 1.7; CI 95%: 0.34-8.54). Moreover, multiple logistic regression analysis did not show any risk or protection factor associated with B. henselae infection in patients with HIV infection. CONCLUSIONS: A high level of seroprevalence of antibodies versus B. henselae was observed in patients with HIV infection. No risk or protection factors associated with B. henselae infection in patients with HIV infection were found.

Adult↗
PubMed1998

[Psoas abscess, a rare and forgotten entity. Report of 6 cases].

The psoas abscess is an entity, some times forgotten in our daily clinical practice. The gram-positive microorganisms are the most frequent, and S. aureus is the most important pathogen. We present a retrospective study of six cases. In our revision, five patients were women (83.3%), and one man (16.6%), with a median age of 65.83 years. The associated pathology were vertebral in four patients (66.6%), and urologic in two of them. The main symptoms were fever and lumbar pain. All the patients were diagnosed by CT. The correct identification of the microorganisms, and the prompt use of the antibiotherapy associated to surgery, helped to a total recuperation of this patients.

Aged↗
PubMed1997

[Scheduled biliary surgery and antibiotic prophylaxis. Is its use always justified?].

AIM: Evaluate the need to give prophylactic antibiotic therapy in patients that undergo elective surgery for cholelithiasis. METHODS: Prospective study in 35 patients the underwent surgery for cholelithiasis, without infectious risk factors. All of them, the hemocultives, endotoxin and Tumor Necrosis Factor has been evaluated along the surgical process. RESULTS: The hemocultives were in all the patients negatives. The levels of Tumor Necrosis Factor decreased along the surgical process, without modifications of endotoxin levels. There were no significant differences in either of the points of the analysis. CONCLUSIONS: Biliary surgery in patients that undergo elective surgery for cholelithiasis, without infectious risk factors, is a clean surgery, and so, in this patients is not indicated systematically an antibiotic prophylaxis.

Antibiotic Prophylaxis↗
PubMed1996

[Evaluation of methods of tick removal in human ixodidiasis].

BACKGROUND: There are two questions regarding tick transmitted diseases (Ixodidae) not sufficiently elucidated: How to remove the arthropod? and: should antibiotic prophylaxis be administered after the bite? SUBJECTS AND METHODS: From June 1st, 1991, to December, 31, 1992, all patients who were attended at La Rioja Hospital relating immediate bite or tick bite within the 48 hours before were prospectively studied. In all those patients an epidemiological inquiry was obtained, which included, apart from personal data and risk factors for tick bites, how arthropods had been removed, health exam and blood drawn for serological study for Borrelia burgdorferi and Rickettsia conorii. The protocol was repeated at one, two, four and six months after the bite. The removal method used at the Hospital was by pulling with fine tweezers and later disinfection with iodine povidone. RESULTS: Out of a total of 52 individuals who complied with the established criteria, only 41 ended the follow-up. A 63.4 percent of patients experienced some type of complication, including 3 cases of LB (erythema migrans). With regard to the type of removal method and the development of complications, only three patients who had ticks pulled with tweezers experienced complications compared with 23 patients who used other methods (p = 0.0058). With regard to specific complications (LB and/or spotted fever) and/or development of B. burgdorferi or R. conorii infection significant differences were also observed when tweezers were used for removal of ticks compared with other tick removal methods (p < 0.05). CONCLUSION: The removal of ticks with tweezers significantly protects from the development of complications and infection by tick-borne microorganisms. Antibiotic prophylaxis is recommended when the removal of the arthropod is carried out by using a method other than the recommended one.

Adolescent↗
PubMed1990

[Evolution of the number of authors in clinical and basic science journals in the Spanish language].

The number of signing authors in Revista Clínica Española. Revista Española de Fisiología and Revista Española de Oncología have been analyzed from their first to the last received issue. The results obtained show an increasing number of authors in all journals specially during the 70s. The results also point out a relative decrease in the number of authors in basic sciences in relation to clinical publications. The increase in the number of authors in The Revista Española de Oncología has started somewhat later than the others. The environmental and professional stress as well as the interrelations between different hospital members have been suggested, amongst others, as the possible cause of these events.

Authorship↗