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Biomedical subjects

J R Blogg

Publications and source records attributed to J R Blogg.

11 recordsLinked to original sources

Multiple striate keratotomy: a treatment for corneal erosions caused by epithelial basement membrane disease.

OBJECTIVE: To study the efficacy of multiple striate keratotomy for the treatment of persistent corneal erosions suspected to be caused by primary corneal epithelial basement membrane disease. DESIGN: A retrospective study. ANIMALS: 16 dogs, three cats and one Australian dingo. PROCEDURE: A technique called multiple striate keratotomy was used to treat twenty animals suffering from persistent corneal erosions. RESULTS: All persistent corneal erosions healed with only one treatment. Most cases healed within 2 weeks. One case developed a second erosion in the same eye but in a different position to the original erosion. CONCLUSIONS: Multiple striate keratotomy is a safe, effective and well tolerated technique for the treatment of persistent corneal erosions thought to be caused by corneal epithelial basement membrane disease.

Animals↗

Eye diseases in Siberian husky dogs.

A full ophthalmic examination was performed on 40 Siberian husky dogs using direct and indirect ophthalmoscopy, gonloscopy and nasolacrimal cannulation. Eight (20%) of the dogs were found to have distichia, 10 (25%) had excessive medial caruncular hairs, 8 (20%) had absence, displacement, or narrowing of the nasolacrimal puncta, 2 (5%) had bilateral corneal crystalline opacities, and 2 (5%) had unilateral areas of lateral corneal lipidosis. Fifty percent of the dogs had some abnormality of the iridocorneal (drainage) angle. However, in only one of these was the deformity severe enough to require glaucoma prophylaxis. An association between blue iris colour and malformation of the iridocorneal angle was noted.

Animals↗

Chloramphenicol 4. Responsible topical use in ophthalmology.

Chloramphenicol has gained widespread use in the topical treatment of ocular infections. The rationale for this use was based on the ability of chloramphenicol to penetrate the cornea and enter the anterior segment, together with its broad spectrum of antimicrobial activity. However, routine use in corneal ulceration or keratitis is not desirable. Hypopyon, when present, is usually sterile. Concerns about human exposure to chloramphenicol and its recent prohibition of use in food-producing animals, raise the need to review its indications and discuss alternatives. The role of chloramphenicol in ocular therapeutics is examined in this article.

Administration, Topical↗

Retinal degeneration in Greyhounds.

Retinal degeneration in 10 Greyhounds with clinical and ophthalmoscopic features is described, including results of electroretinography and fluorescein angiography for one affected dog. Clinical and histologic features differed from other kinds of retinal degeneration in dogs.

Animals↗

Keratoconjunctivitis sicca in dogs associated with sulphonamide administration.

This report describes the clinical characteristics of 14 cases of sulphonamide-induced keratoconjuctivitis sicca in dogs. Two drugs, sulphadiazine and salicylazosulphapyridine, were associated with the disease. It is recommended that Schirmer Tear Test be performed regularly when sulphonamides are administered long term to dogs. The hypothesis that a nitrogen-containing pyridine ring is responsible for the lacrimotoxic effect is advanced.

Animals↗