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Biomedical subjects

J R Brow

Publications and source records attributed to J R Brow.

6 recordsLinked to original sources
PubMed1989

Lymphoma pancreatitis: a real entity.

Pancreatitis induced by malignant disease is uncommon. A case of lymphoma presenting as acute pancreatitis and subsequent pancreatic abscess is reported; this led to the patient's death, 6 weeks after the initial attack of pancreatitis. Five other reports are reviewed. The pancreatitis always preceded the diagnosis of lymphoma and the preoperative diagnosis was always difficult. Lymphoma pancreatitis should, therefore, be considered in the etiology of acute pancreatitis, especially if the more likely causes have been ruled out.

Abdominal Neoplasms↗
PubMed1984

Surgical management of primary bile-duct carcinoma.

Primary bile-duct carcinoma is a rare lesion, causing death from hepatic failure due to biliary obstruction. Between 1976 and 1983, 22 patients with this tumour were treated at the Sunnybrook Medical Centre in Toronto. Thirteen patients had unresectable proximal bile-duct carcinoma of the high type. Distal bile-duct carcinomas in three patients were not resected because of metastatic disease. Three proximal bile-duct carcinomas of the low type and three distal bile-duct carcinomas were resectable. A new method of internal biliary decompression is presented, for palliation in patients with proximal bile-duct carcinoma of the high type. An intraluminal polyethylene stent has produced satisfactory quality of life with a mean survival of 16 months in eight patients; two others are alive with disease, 9 and 19 months after placement of a stent. Satisfactory palliation of distal, unresectable lesions can be achieved by biliary intestinal anastomosis in some cases.

Adenoma, Bile Duct↗
PubMed1981

Resection for chronic alcoholic pancreatitis.

Nineteen patients with chronic alcoholic pancreatitis have been followed up for 7 to 81 months (mean 45 months) since resection for the relief of pain. Five had distal pancreatectomy, three had a Whipple resection, seven had 75% pancreatectomy and four had total pancreatectomy. Pain was completely relieved in all patients after total pancreatectomy and in four patients after 75% pancreatectomy. Recurrent acute pancreatitis was frequent after distal pancreatectomy. Alcoholism recurred in six patients. Steatorrhea was noted grossly in 14 patients after operation. It was corrected by enzyme replacement. All patients had long-term weight gain, except one who had undergone a Whipple resection. Diabetes developed in one patient who underwent 75% pancreatectomy, in one after distal pancreatectomy and in all patients who underwent total pancreatectomy; management of the diabetes was complicated by heavy alcohol consumption in one patient who underwent total pancreatectomy.

Adult↗