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Biomedical subjects

J R Kamat

Publications and source records attributed to J R Kamat.

7 recordsLinked to original sources

AIDS with special reference to pediatric aspect.

The article discusses the disease AIDS, and its increasing incidence all over the world. The alarming rise of HIV infection amongst those tested in India is noted. The projection as made by WHO are mentioned. The various modes of transmission of HIV infection and the high risk groups for each mode are identified. Clinical manifestation of an adult case is followed by that of a pediatric patient in whom the infection is mostly transplacental. The risk of TAA amongst children is highlighted as also the difference between adult and pediatric AIDS. Diagnosis of AIDS, its management, prognosis and prevention are mentioned. The similarity between HIV-1, SIV and HIV-2 induced immunodeficiency is recorded.

Acquired Immunodeficiency Syndrome

Polymorphonuclear leukocyte functions in patients with acute rheumatic fever and rheumatic heart disease.

Polymorphonuclear (PMN) cell function was assessed in 30 children with active rheumatic fever (ARF) (Group I), 30 cases with active rheumatic heart disease (RHD) (Group II), 28 cases of ARF and RHD in remission (Group III) and 34 adults with quiescent RHD along with their age matched controls. All the groups showed normal spontaneous and chemotactic movement. Phagocytosis of yeast particles was significantly reduced in groups II (P less than 0.0005), III (P less than 0.025) and IV (P less than 0.005). The opsonic activity of disease sera was low in all 4 groups (P less than 0.0005). The intracellular metabolic activity was moderately elevated in Group III. Phagocytosis and opsonic activity were thus persistently low in all the groups including the remission and quiescent group.

Adolescent

Imprint cytology in the diagnosis of breast tumor.

Fifty breast lumps seen and operated on at the Goa Medical College Hospital over a one year period form the material for this study. The cases were at first diagnosed clinically. At operation a naked eye assessment of the malignancy of the excised breast lump was made. Slide imprints for cytodiagnosis were made and finally the excised mass sent for paraffin section study. A rapid diagnosis of these 50 surgically removed breast lumps was thus made by naked eye examination and imprint cytodiagnosis and the results were compared with routine paraffin section diagnosis which is considered the final diagnosis. An analysis of the results show that naked eye examination of the excised breast lump distinguished between malignant and non-malignant lumps correctly in 96% of cases, rapid imprint cytodiagnosis was correct in 98% of cases, clinical diagnosis in 96% of cases and aspiration cytodiagnosis in all cases. Naked eye examination of the mass prior to imprinting would help to decide the correct pressure to be used to avoid false results.

Breast Neoplasms