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J R Kirkwood

Publications and source records attributed to J R Kirkwood.

9 recordsLinked to original sources

Recognition of vertebral fracture in a clinical setting.

Osteoporosis-related vertebral fractures have important health consequences for older individuals, including disability and increased mortality. Because these fractures can be prevented with appropriate medications, recognition and treatment of high-risk patients is warranted. A cross-sectional survey was carried out in a large, regional hospital in New England to examine the frequency with which vertebral fractures are identified and treated by clinicians in a population of hospitalized older women who have radiographic evidence of fractures. The study population consisted of 934 women aged 60 years and older who were hospitalized between October 1, 1995 and March 31, 1997, and who had a chest radiograph obtained. Vertebral fractures in the thoracic region were identified by two radiologists. Discharge diagnoses, medical record notes and radiology reports were compared with the results of the radiologists' readings to determine the frequency with which fractures were identified and appropriate, osteoporosis-preventing medications prescribed. Moderate or severe vertebral fractures were identified for 132 (14.1%) study subjects, but only 17 (1.8%) of the 934 participants had a discharge diagnosis of vertebral fracture. Of these 132, only 17% had fracture noted in the medical record or discharge summary; 50% of contemporaneous radiology reports identified a fracture as present; and 23% of the time it was found in the radiologist's summary impression. Only 18% of medical records indicated that fracture patients had been prescribed calcium, vitamin D, estrogen replacement or an antiresorptive agent. Relatively few hospitalized older women with radiographically demonstrated vertebral fractures were thus identified or treated by clinicians, suggesting a need for improved recognition.

Aged↗

Computed tomographic studies of the head in a teaching hospital and a community hospital: a comparison.

This investigation compared the use of computed tomography (CT) of the head at a large primary medical-school-affiliated hospital and at a large community hospital. There were two aims: first, to study the intrinsic characteristics of the patients in an attempt to determine the potential for developing accurate discrimination algorithms; and second, to study the patterns of neurodiagnostic tests used at these facilities. The results indicated that separability of patients into normal and abnormal categories at both institutions was extremely small. In addition, there was no significant difference in the numbers of types of ancillary tests used at both institutions. Overall, these data once more confirm the difficulty of altering CT usage patterns in primary or secondary hospitals without significantly affecting the number of abnormal patients identified.

Boston↗

The posterior cerebral radionuclide angiogram for the detection of carotid artery disease.

To determine the accuracy of the posterior cerebral radionuclide angiogram (CRAG) in the detection of carotid occlusive disease, a retrospective study of 186 patients who underwent both CRAG and contrast cerebral angiography within a period of 30 days was carried out. Asymmetry of neck activity was highly specific (97%) but insensitive (27%) for detection of carotid disease. When asymmetry of cerebral perfusion was also considered, the sensitivity rose to 61%, but the specificity fell to 77%. For the entire group, including carotid and intracerebral disease, the sensitivity of the posterior CRAG was 49% and the specificity 89%. From these data and a review of the literature, we conclude that the CRAG is too insensitive to be used as a screening test for carotid occlusive disease.

Arterial Occlusive Diseases↗

Posterior fossa hemorrhage. Localization by computerized tomography.

The differentiation between pontine and cerebellar hemorrhage is important both prognostically and therapeutically but is often very difficult. Computerized axial tomography of the brain is a new, rapid, nonivasive method of studying intracranial disease. This technique proved useful in making this important differential diagnosis in the case reported here.

Cerebral Hemorrhage↗