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Biomedical subjects

J R Knight

Publications and source records attributed to J R Knight.

8 recordsLinked to original sources
PubMed1991

Knowledgeable non-compliance with prescribed drugs in elderly subjects--a study with particular reference to non-steroidal anti-inflammatory and antidepressant drugs.

Knowledgeable non-compliance with non-steroidal anti-inflammatory drugs (NSAIDs) and antidepressant drugs was investigated in a community-based sample of elderly people. Everyone 70 years and over living in a defined area and taking one of the above drugs, and at least one other prophylactic or symptomatic drug, was studied. Non-steroidal anti-inflammatory drugs and antidepressant drugs are commonly regarded as symptomatic only and knowledgeable non-compliance is consequently high. They are also regarded as less important than drugs which produce no immediate relief of symptoms but which the patient recognizes as needing to be taken regularly to maintain health. In our study, compliance with non-steroidal anti-inflammatory drugs and antidepressant drugs was highest in those who were compliant with a prophylactic drug and were also taking a symptomatic drug. The greater the number of tablets the patient was taking the more likely he or she was to be compliant with the NSAID. Compliance with NSAIDs and antidepressant drugs requires clear label instructions and the patient knowing the purpose of the medication.

Aged↗
PubMed1986

Usefulness of the ergometric testing in patients with the long Q-T syndrome.

Fifty patients with an exercise test positive for coronary artery disease (CAD) were analyzed for the presence of a long Q-T interval corrected for heart rate (Q-Tc). While there were only 3 patients with a long Q-Tc (6%) in the resting ECG, with the exercise test their number increased to 12 (24% of the total). If the test could not be done, such subjects were considered to have CAD and normal Q-T intervals. This is of great importance because patients with normal Q-T intervals are treated with group I antiarrhythmic drugs, whereas these drugs are contraindicated in patients with long Q-T intervals.

Adult↗
PubMed1975

Review of computer applications in hospital pharmacy practice.

A comprehensive literature review of the applications of computers in hospital pharmacy practice is presented. Articles are categorized as: accounting and drug usage review; purchasing and inventory control; controlled substances; outpatient services;drug distribution; drug information; and clinical services.

Accounting↗