PubMed Health⌕ Search

Biomedical subjects

J R Leonidas

Publications and source records attributed to J R Leonidas.

15 recordsLinked to original sources
PubMed1987

Hair alteration in black patients with the acquired immunodeficiency syndrome.

Four black men with the acquired immunodeficiency syndrome (AIDS) demonstrated profound alterations in hair patterns two to three years after their first symptoms appeared. The hair became longer, lighter, softer, and silky, and it was occasionally discolored. One patient was thought to be of Indian extraction. These changes may not be as apparent in nonblack persons. Possible explanations are a retrogression of hair pattern to an earlier stage of growth, a phenomenon reminiscent of, but not similar to, malnutrition trichosis, or a combination of both. Closer attention should be paid to the hair of AIDS patients. Histologic and chemical analysis may be appropriate.

Acquired Immunodeficiency Syndrome↗
PubMed1985

Cervical lipomas masquerading as thyroid nodules.

Masses in the thyroid gland can usually be distinguished from other anterior cervical masses by history, physical examination, and scintigraphic and ultrasonographic examination. We describe four cases of lipomas masquerading as thyroid nodules in which finding from these examinations were consistent with solid thyroid nodules. Computed tomography can distinguish fat from thyroid tissue density, thus avoiding the use of thyroid hormone suppression or the need for urgent surgery.

Adult↗
PubMed1983

A case of pantaloon obesity.

A 79-year-old woman presented with an unusual form of obesity limited to the lower half of the body from the waistline down but sparing the lower legs and feet. The patient was massive (360 lbs) and symmetrical. The superior half of the body was normal with no morbid obesity or lipoatrophy. These findings do not correspond to any classic form of lipodystrophy. The fat distribution is reminiscent of a pair of knickers and qualifies for the name "pantaloon obesity."

Aged↗
PubMed1981

Endocrine studies in a patient with functioning adrenal rest tumor of the liver.

We report a case of a calcified liver tumor in a 23 year old female patient who presented with virilization and a mild degree of Cushing's syndrome. Androgen levels were elevated; there was loss of cortisol circadian rhythm and marked increase in urinary 17-ketogenic and 17-ketosteroids which failed to suppress with administration of dexamethasone. Venous sampling by inferior vena cava catheterization showed that the highest steroid hormone levels were in blood from the right hepatic vein. After death, in vitro studies revealed that the tumor contained testosterone and cortisol as determined by immunofluorescence techniques. The adrenals and ovaries were atrophic. Results of metyrapone testing indicated dyshormonogenesis. To our knowledge, this is the first case of an adrenal rest tumor of the liver proved to be functionally active.

Adrenal Rest Tumor↗