Biomedical subjects

J R Locke

Publications and source records attributed to J R Locke.

5 recordsLinked to original sources

PubMed1988

Suppurative pylephlebitis caused by toothpick perforation.

We have reported a case of suppurative pylephlebitis in an elderly, debilitated patient. The infection was caused by toothpick perforation of and migration from the gastrointestinal tract. The patient had risk factors for foreign body ingestion, including poor dentition, aphasia caused by a previous cerebrovascular accident, and alcohol abuse. Investigation for the otherwise obscure cause of suppurative hepatic disease should take into account the possible, yet difficult to define, source related to an ingested foreign body.

Aged↗

PubMed1987

Management of obstruction and resultant complications in transplant kidney by endoscopic and percutaneous techniques.

Management of obstructive complications in a renal transplant patient are most efficiently performed using endoscopic and percutaneous techniques where possible. A case of such obstruction managed by placement of an internal stent is described. An unusual complication involving the fracture of the stent was also managed percutaneously.

Adolescent↗

PubMed1987

Megalourethra: surgical technique for correction of an unusual variant.

We report a case of an unusual variant of megalourethra associated with urethral duplication. The surgical technique for an enlarged and massively deformed phallus is described.

Humans↗

PubMed1986

Osteogenic differentiation associated with x-ray therapy for adenocarcinoma of the prostate gland.

A case of osteogenic differentiation in a prostate gland associated with high-dose x-irradiation for adenocarcinoma is reported. Heterologous cancerous elements in adults are extremely unusual in the prostate and their occurrence after treatment has rarely been documented. The relationship of this lesion to the primary glandular neoplasm is discussed.

Adenocarcinoma↗

PubMed1985

Incidence of squamous cell carcinoma in patients with long-term catheter drainage.

Long-term indwelling catheters constitute a risk factor for the development of bladder malignancy. We assessed prospectively by bladder biopsy and urine cytology 25 consecutive spinal cord injury patients catheterized for a minimum of 10 years. Two cases of squamous cell carcinoma of the bladder were identified. Both patients with cancer had positive cytology findings and hematuria, suggesting that routine bladder biopsy in the asymptomatic patient may not be warranted. The high risk of malignancy (8 per cent) in these patients is yet another compelling reason to minimize the use of long-term indwelling catheters.

Carcinoma, Squamous Cell↗