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J R Logic

Publications and source records attributed to J R Logic.

At least 19 recordsLinked to original sources
PubMed1994

CSF otorrhea.

Explore the source record for details and available documents.

Cerebrospinal Fluid Otorrhea↗
PubMed1984

Results of radionuclide assessment of cardiac function following transplantation of the heart.

Radionuclide assessment of ejection fraction was determined early and late postoperatively following cardiac transplantation in 16 patients. In 11 patients, ejection fraction was determined within 48 hours of an endocardial biopsy. There was no relationship between the severity of histologically evident rejection and the ejection fraction (Pearson correlation coefficient [r] = -0.11; p = 0.47). In 2 patients, severe graft fibrosis developed with consequent diminution in ejection fraction. There was no relationship between severity and duration of rejection or the amount of immunosuppression required to treat acute rejection and the development of graft fibrosis. The mean resting ejection fraction in 7 patients in follow-up ranging from 6 to 21 months after transplantation was 0.59 +/- 0.06 (standard deviation), and the mean exercise ejection fraction in 6 of these patients was 0.72 +/- 0.08. Radionuclide-determined ejection fraction is not predictive of rejection early after operation. During short-term late follow-up, systolic left ventricular function at rest and exercise has been retained at normal levels.

Heart↗
PubMed1984

Gallium-67 scanning in Sjögren's syndrome: concise communication.

We performed gallium-67 scans in 12 patients with primary or secondary Sjögren's syndrome (SS). Salivary-gland uptake of gallium-67 was noted in four of five patients with primary SS. Pulmonary uptake was observed in ten of 12 patients. Chest radiographs were essentially normal in all patients, although 60% complained of significant dyspnea with exertion. The gallium-67 scan may prove to be a sensitive noninvasive diagnostic test for lung and mediastinal involvement by either primary or secondary SS, and for salivary-gland involvement in primary SS.

Adult↗
PubMed1982

Radionuclide angiography in the evaluation of ductal shunts in preterm infants.

Radionuclide angiograms were compared with radiographic and physical findings and with echocardiographic left atrial to aortic ratios in 30 neonates clinically suspected of having a persistent ductus arteriosus. In three infants without clinical signs and with normal LA/Ao ratios (10%), radionuclide angiograms provided evidence of a large left-to-right shunt, which was confirmed by the finding of a large ducts arteriosus at surgery. Whereas routine physical, radiographic, and echocardiographic criteria fail to identify some neonates with large PDA's, the present study suggests that radionuclide angiography can be performed in a neonatal intensive care unit setting and may be a valuable addition to currently employed diagnostic techniques.

Angiography↗
PubMed1981

Measurement of effective renal plasma flow in congestive heart failure.

In the management of patients with congestive heart failure (CHF), it is often desirable to have precise knowledge of overall renal function, including the effective renal plasma flow (ERPF). It has long been recognized that ERPF is diminished in CHF. Since glomerular filtration rate is often decreased to a much lesser extent, other noninvasive procedures such as the measurement of creatinine clearances may not be entirely suitable. ERPF determination by the single plasma sampling (SPS) method affords a rapid, simple, noninvasive, and economical technique that is quite accurate and reproducible. A SPS method has been well-tested in patients following renal transplantation plus a wide variety of nephrological disorders. We have been concerned whether the SPS method would be valid in volume expanded patients. In 28 determinations of ERPF in patients with CHF, and in five patients who did not have CHF, we have found the SPS estimation of ERPF to yield results that are not clinically significantly different from those obtained by the detailed compartmental analysis method. The volumes of 131I-orthoiodohippurate (OIH) distribution were found to be somewhat higher in CHF than in controls, but fractional rate constants were proportionately lower so that intercompartmental flow rates and OIH concentrations were not different from controls. Therefore, the SPS estimation of ERPF is valid in patients with CHF and may be useful in monitoring the renal effects of various hemodynamic and pharmacological interventions.

Adult↗
PubMed1981

Maximizing the information from thallium studies.

The clinical role of maximizing the value of T1-201 scintigraphy, both at rest and during a graded exercise tolerance test, as well as variations on that theme, have been described. Technical aspects of scintigraphy have been reviewed in view of the many complex properties of this radionuclide, including photon detection and attenuation. Rest studies may be important in acute myocardial infarction to predict complications, survival, and reoccurrence. The potential for stress testing has been emphasized, as well as the apparent problems of such studies in patients at high-risk, such as those with definite angina and post-coronary by-pass surgery. A comprehensive approach to the complementary or exclusionary nature of T1-201 (or other potential myocardial perfusion imaging agents) and ventricular function analysis using radionuclide techniques will be left to the present and future seers, which, of course, hopefully include this author and his associates.

Angioplasty, Balloon↗
PubMed1979

Incidence of new pulmonary perfusion defects after routine cardiac catheterization.

The incidence of pulmonary perfusion defects after routine cardiac catheterization was assessed in 57 patients by comparing ventilation-perfusion lung scans obtained before and 1 day after catheterization. Patients were prospectively randomized to two groups, one in which right heart catheterization was performed using an antecubital venous cutdown procedure and one in which the percutaneous femoral vein approach was used. Seven patients (12 percent) had new postcatheterization perfusion defects consistent with pulmonary emboli. These patients did not differ significantly from patients without new defects in clinical characteristics, duration of catheterization, hemodynamic variables or route of right heart catheterization. The data suggest that pulmonary embolism may be a more common complication of routine cardiac catheterization than previously appreciated.

Adult↗
PubMed1979

Usefulness and limitations of thallium-201 myocardial scintigraphy in delineating location and size of prior myocardial infarction.

In order to evaluate the usefulness of thallium-201 (201TI) myocardial scintigraphy in delineating the location and size of prior myocardial infarction, 32 patients were evaluated at a mean of 7 +/- 2 months after infarction with a 12-lead ECG, resting 201TI myocardial scintigram, biplane left ventriculogram and coronary angiograms. From the left ventriculogram, asynergy was quantified as percent abnormally contracting segment (% ACS), the percent of end-diastolic circumference which was either akinetic or dyskinetic. Using a computerized planimetry system, we expressed 201TI perfusion defects as a percentage of total potential thallium uptake. Of 21 patients with ECG evidence of prior transmural infarction, a 201TI defect was present in 20 (95%), and angiographic asynergy was present in all 21 (100%). The site of prior infarction by ECG agreed with the 201TI defect location in 24 of 32 patients (75%) and with site of angiographic asynergy in 23 of 32 patients (72%). Scintigraphic defects were present in only four of 10 patients (40%) with ACS less than or equal to 6%, but scintigraphic defects were found in 20 to 22 patients (91%) with ACS greater than 6% (p less than 0.01). Thallium defect size correlated marginally with angiographic left ventricular ejection fraction (r = -0.60) but correlated closely with angiographic % ACS (r = 0.80). Thallium defect size was similar among patients with one-, two-, or three-vessel coronary artery disease (greater than or equal to 70% stenosis), but thallium defect size was larger in patients with electrocardiographic evidence of transmural infarction (p less than 0.01) or pulmonary capillary wedge pressure greater than 12 mm Hg (p less than 0.001). Thus, resting 201TI myocardial scingigraphy is useful in localizing and quantifying the extent of prior myocardial infarction, but is insensitive to small infarcts (ACS less than 6%).

Angiocardiography↗