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Biomedical subjects

J R Lyall

Publications and source records attributed to J R Lyall.

7 recordsLinked to original sources

Fibreoptic bronchoscopy under general anaesthesia using the laryngeal mask airway.

The laryngeal mask airway was used to facilitate fibreoptic bronchoscopy under general anaesthesia in 140 adult patients. Following placement, the position of the mask was observed through the fibreoptic bronchoscope. Three different positions were identified. In 120 patients (86%) the concave surface of the mask faced the larynx directly with or without some unfolding of the epiglottis. In 17 patients (12%) the laryngeal mask appeared to be at an angle facing one pyriform fossa and in two patients the tip of the mask lay anterior to the arytenoids. No problems with ventilation or maintenance of an acceptable airway were encountered. In one patient repositioning of the laryngeal mask was necessary to allow the passage of the bronchoscope. One patient developed laryngospasm and required tracheal intubation.

Adolescent↗

Sequential brush biopsy and conventional biopsy: direct comparison of diagnostic sensitivity in lung malignancy.

One hundred and sixteen patients with suspected lung malignancy who were referred for bronchoscopy were examined using both the flexible fibreoptic bronchoscope and the rigid bronchoscope. Both instruments were used sequentially under the same general anaesthetic. Brush biopsies were obtained through the fibreoptic bronchoscope and conventional biopsies, for histological examination, through the rigid bronchoscope. Both specimens were taken from the same area. Eighty-two per cent of those in whom there was a final clinical diagnosis of malignancy were found to have abnormal cytology via the fibreoptic bronchoscope, while abnormal histology was found in 50% by means of the rigid bronchoscope. For those in whom malignancy was confirmed, 16.9% showed disagreement between the two methods in cell typing. Brush biopsy through the flexible fibreoptic bronchoscope under general anaesthesia is confirmed as a sensitive method for diagnosing lung malignancy.

Adolescent↗

Ventilation-perfusion lung scans for pulmonary emboli. Accuracy of reporting.

Reports were made on combined ventilation-perfusion lung scans by three observers on three occasions and by another observer once. Reproducibility for each observer varied between 80 and 88%. There was complete agreement about the areas of scans reported as abnormal. Agreement between observes on whether or not the abnormality represented a pulmonary embolus averaged 77%. There was 86% agreement with the final clinical diagnosis. Our results show that reporting of ventilation perfusion lung scans by eye is reproducible. They support the claims that, under routine clinical conditions, the technique is 91% to 95% accurate for pulmonary emboli.

Humans↗