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Biomedical subjects

J R Munns

Publications and source records attributed to J R Munns.

4 recordsLinked to original sources
PubMed1989

Prolonged ventricular support using a centrifugal pump.

The Biomedicus centrifugal pump was required to provide prolonged ventricular support to 13 patients with hemodynamic instability: 11 after cardiovascular surgical procedures, 1 after myocardial infarction and 1 after failure of a heart transplant. The duration of support ranged from 3.5 hours to 9 days (mean 72 hours). Complications included bleeding in six patients, renal insufficiency in three and central nervous system deficit in three. Six patients (46%) were successfully weaned from the pump. The patient with graft failure had hyperacute rejection of a second heart. Five patients were discharged from the hospital. There was one death 8 months postoperatively. Prolonged ventricular support with the centrifugal pump may allow recovery of potentially reversible ventricular dysfunction in selected patients after cardiac surgical procedures.

Adolescent↗
PubMed1976

Effect of gastric bypass on gastric secretion.

Gastric bypass as a 90 per cent gastric exclusion operation was used in 393 patients with massive obesity to limit food intake. Stomal ulcer has occurred in 1.8 per cent of such patients or one ulcer per 140 man years of observation. The studies of indwelling fundic pH and of gastric acid secretion from the excluded stomach indicate that acid secretion is reduced after gastric bypass but that the acid, unbuffered by food in the excluded stomach, results in a lowered gastrin secretion after a meal. Thus, gastric bypass in inhibitory to acid secretion in most morbidly obese patients who do not have known acid peptic disease.

Achlorhydria↗
PubMed1975

Aneurysmectomy in the aged.

The records of 206 aneurysmectomy patients over the age of 70 years were reviewed. Increased three- and five-year mortality was seen with a variety of risk factors--cerebral vascular disease, cardiac disease, diastolic hypertension, renal disease, and cigarette smoking--but 30-day mortality was not affected. Age was not a significant risk factor. It is recommended that patients with aneurysms less than 7.5 cm be observed if multiple risk factors are present. Almost all patients with aneurysms greater than 7.5 cm should have resection to prevent death from rupture, although this will be short-term palliation in patients with multiple risk factors.

Age Factors↗