Byssinosis in developing countries.
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Biomedical subjects
Publications and source records attributed to J R Parikh.
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An epidemiological study was carried out in three textile mills of Ahmedabad. A total of 214 cotton dust exposed and 184 control subjects were examined for pulmonary function tests. Pulmonary function tests included forced vital capacity and forced expiratory volume in one second. The pulmonary function tests were carried out before starting the shift and after 7 hours of exposure on a vitalograph spirometer. The study shows that among the cotton dust exposed workers byssinotics behave distinctly and show the maximum acute and chronic changes in pulmonary functions. It seems that the effect of cotton dust exposure on the byssinotic subjects is more predominant than the effect of smoking.
In an epidemiological study carried out in three textile mills at Ahmedabad, India, 929 workers were examined from the spinning departments. The mean prevalence of byssinosis in the blow section was 29.62%, whereas in the card section it was 37.83%. The concentrations of cotton dust (dust less fly) were high in the blow and card sections (4.00 mg/m3 in the blow and 3.06 mg/m3 in the card section). This study suggests that the prevalence of byssinosis is not low in the textile mills of India as reported in many earlier Indian studies.
Occupational sickness among tobacco farmers due to the handling of green tobacco leaves is termed "green symptom." This symptom was investigated among 197 Indian tobacco workers and it was found that 88.83% of the workers were suffering from green symptom when exposed to green tobacco leaves during their occupational operation. Nicotine concentration of the urine was estimated only among male subjects who were smokers. During the exposure period (when subjects were suffering from green symptom), more than a three-fold increase in nicotine concentration in the urine was observed. Both cured and uncured leaves may cause such sickness.
The use of rubber gloves reduced nicotine and cotinine absorption among 29 tobacco harvesters, as evidenced by the urinary excretion rate of nicotine and cotinine. Approximately 20% (n = 6) of the subjects reported that symptoms disappeared when they used gloves, but the remaining 23 workers complained of an occasional headache even when using gloves. Wearing of boots and socks as well as gloves prevented the symptoms and significantly decreased nicotine and cotinine excretion. This suggests that nicotine is absorbed through the feet.
Static CT is of established value in evaluating the knee joint. The use of knee manipulation followed by repeat CT to establish a definitive diagnosis has not been previously described. An illustrative case is presented.