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Biomedical subjects

J R Paskins

Publications and source records attributed to J R Paskins.

4 recordsLinked to original sources

Management of partial thickness burns with Granuflex 'E' dressings.

In a prospective, open, randomized and parallel group trial, 98 patients with partial thickness burns suitable for outpatient management were treated with either Granuflex 'E' (n = 49) or Bactigras (n = 49). The objective was to compare the safety, efficacy and performance characteristics of Granuflex 'E' with Bactigras. The overall rating of the dressing by the investigators and the patients showed a significant preference for Granuflex 'E'. In addition, the quality of healing was rated as 'excellent' in 56 per cent of patients treated with Granuflex 'E', compared with only 11 per cent in the group treated with the conventional dressing. Granuflex 'E' is safe, effective and flexible and we recommend that it should be used as the first-choice dressing in the management of partial skin thickness burns.

Biological Dressings↗

The effect of ketamine anesthesia on anorectal manometry.

Two hundred and twenty-five patients aged from neonate to 15 years presenting with chronic constipation and soiling had anorectal manometry without sedation, and 142 patients in the same age range and with a similar range of presenting complaints had anorectal manometry using ketamine as an anesthetic. There were no significant differences between the groups in the resting pressures recorded in the anal canal, in the amount of inhibition with rectal distension, or in the frequency or amplitude of rhythmical activity of the internal anal sphincter. Classical inhibitory troughs were seen when expected in both groups as were signs of external sphincter activity. Ketamine anaesthesia is a suitable sedative which enables anorectal manometry to be performed on young or nervous patients and does not alter the qualitative or quantitative responses.

Adolescent↗