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Biomedical subjects

J R Poleo

Publications and source records attributed to J R Poleo.

At least 19 recordsLinked to original sources

[Non ulcer dyspepsia, endoscopic gastritis and Helicobacter pylori].

We studied 33 patients with non ulcer dyspepsia and endoscopic gastritis. 21 were female (63.4%) and 12 male (36.4%). Helicobacter pylori (HP) was investigated by gastric mucosal biopsy. Urease test, Gram, culture, and histology were performed in all and two or more of these test hat to be positive to consider HP infection. 16/33 resulted HP positive (48.8%). Erosive gastritis was most commonly associated with H.P. infection (62.5%). This was statistically significant. In all the cases HP positive chronic gastritis was present. 15/16 were active chronic gastritis. Our results suggest that erosive gastritis is most frequently associated with HP infection and non ulcer dyspepsia.

Adolescent↗

[Nonulcerative dyspepsia associated with Helicobacter pylori].

30 patients with non ulcer dyspepsia (NUD) were evaluated to find out if there was a relationship with Helicobacter pylori (HP) infection. Gastric biopsies from the antrum were taken and two of them sent to pathology to be stained with H&E and Warthin-Starry. The other three were sent to Microbiology, for urease-test, culture and frotis with Gram stain. To diagnose HP was necessary to get it at least in two of the performed test. This was possible in 20 (66.66%). Chronic active gastritis was observed in 15/20 (75%) and in the 3/10 HP negative patients none had histological alteration shown. Normal aspect of gastric mucosa did not predict Helicobacter pylori infection. The presence of the bacteria could not be correlated to any kind of symptoms and always was associated with chronic gastritis.

Adolescent↗

[Jejunal leiomyosarcoma. A case report].

Jejunal leiomyosarcoma, is an uncommon neoplasm. Diagnosis can be difficult because symptoms may be vague and nonspecific. We report the case of a 33-years-old patient, which was diagnosed and operated of this infrequent pathology.

Adult↗

[Value of three-dimensional measurement of the caudate lobe in the diagnosis of liver cirrhosis by ultrasound].

To assess the changes of the caudate lobe in the sonographic diagnosis of liver cirrhosis, 96 patients were studied at the Hospital Vargas de Caracas. 27 with histologically proved cirrhosis. 43 with other disease (30 no related with liver and 13 with hepatic disease without cirrhosis, and 26 patients without clinical evidence of liver disease. The longitudinal (CL), transverse (CT), and anteroposterior (CAP) diameters of the caudate lobe and the transverse diameter of the right lobe (RL) were measured and one, two and three dimensional caudate lobe, indexes and ratios were calculated. The analysis of these criteria revealed that the ratio of the three dimensional caudate index (C13) to the right lobe diameter (C13)/RL = iCL x CT x CAP/RL was superior to all other calculated criteria.

Adolescent↗

[Retrograde endoscopic cholangiopancreatography. Incidence of bacteremia].

ERCP like all the endoscopic procedures, implies some risks of complications, between them, infections. Bacteremia may occur in any endoscopic and gastrointestinal procedure. The rate on ERCP is about 0 to 5.6%. In the present investigation we intended to determine the rate of bacteremia produced by ERCP, the organism that cause bacteremia and to correlate ductal pathology, stasis and bacteremia. From May to October 1988, at the Hospital Vargas of Caracas, 22 ERCP were performed in patients that were included for analysis. Haemocultives were taken for aerobics and anaerobics, gems before ERCP, immediately after the cannulation of biliary and/or pancreatic ducts and 5 minutes later after concluding the study. A high incidence of bacteremia was reported, 13.6%, all the previous haemocultives were negative. The positive haemocultives were during the cannulation procedure and no haemocultive after the study was positive. The organism isolate were Peptococcus sacharoliticcus and Staphylococcus epidermidis both of the normal flora of small intestine and the last one on the skin too. There were not relation between the ductal pathology, stasis and bacteremia. Some organisms were related to nosocomial agents, we considered though the disinfection and polishment of the accessories and equipment adequate. It is recommendable to use prophylactic antibiotic in immunosuppressed patients with valvular prosthesis.

Adult↗

[Barrett esophagus. Frequency, endoscopic, histologic, and clinical characteristics].

We reviewed 9210 upper gastrointestinal endoscopic examinations during a 66 month period and found 23 (0.24%) diagnosis of Barrett's Esophagus (BE). Male/female ratio was 1.3:1. Age was 23-79 year old (y/o) mean 50.60 y/o. Histological diagnosis was confirmed in 23/35 cases and cardiac type was present on 60.86%, intestinal type in 39.10%. Dysplasia was not found. Endoscopic mucosal lesions were: finger-like projections 13/23 (56.52%), ulcers in five cases (21.73%), islands of columnar epithelium and circumferential extension in 2 each (8.69%), and stenosis in one (4.34%). The low frequency in this series could be attributed to a retrospective analysis. The high risk for developing adenocarcinoma of the esophagus justifies prospectives trials in our country to verify the prevalence.

Adult↗

[Percutaneous liver biopsy in outpatients].

We studied prospectively 44 patients with diffuse liver disease. We performed percutaneous liver biopsy in these outpatients. They were required to be in absolute response during the following 4-6 hours after the biopsy was completed. After that period, they could go home and have a relative rest for the remnant day. These patients were followed by clinical evaluation and by real time abdominal ultrasound. We found some complications: Transitory arterial hypotension, pain in the site of puncture, hepatic hematomas. Only one of the patients with hematomas required hospitalization during 24 hours. The mortality was 0%. According to our experience, the hepatic biopsy is a procedure that can be performed in outpatients with a wide margin of security. An important point of view to consider is the economic advantage since it means a decrease in costs by each hepatic biopsy accomplished considering the cost/day of hospitalization.

Adolescent↗

[Budd-Chiari syndrome, pulmonary thromboembolism, and deep venous thrombosis associated with "lupus anticoagulant" and recent use of oral contraceptives].

The Budd-Chiari syndrome is the clinical manifestation of the total or partial obstruction of the hepatic veins and/or inferior vena cava. It is an infrequent cause of portal hypertension. The chronic presentation is the most frequent and is characterized by right upper quadrant pain, hepatomegaly, and ascites of slow onset. We report a case of a 26 year old woman affected by this disorder associated to a recent use of oral contraceptive and a "Lupus Anticoagulant". She subsequently developed deep venous thrombosis and pulmonary embolism. She died almost 6 years after the onset of symptoms.

Adult↗

[Frequency of Campylobacter pylori in apparently healthy and asymptomatic Venezuelans].

We evaluated 21 healthy asymptomatic Venezuelan volunteers free of risk factors for gastritis with upper gastrointestinal endoscopy, and four antral biopsies: a)2 for histological examinations, b) Urease test, c) culture and gram coloration. 13 out of 21 subjects were positive for Campylobacter pylori (61.30%) all of them had chronic gastritis and in the negative cases 7 were considered histologically normal. Urease test was positive in 12/13 with a sensitivity of 92% and 100% specificity. Frequency in our series is high for Campylobacter pylori (61.30%) and this justify prospective and massive study of the population to detect de prevalence in our country with simpler and cheaper methods.

Adult↗

[Value of ultrasound and retrograde pancreatocholangiography in the diagnosis of pancreatic diseases].

26 patients with pancreatic disease were studied with ultrasound (US) and endoscopic retrograde cholangiopancreatography (ERCP). Results were compared in terms of selectivity, sensibility and specificity. In spite of similarity of both techniques regarding selectivity and sensibility, US appeared to be more specific. Combination of US and ERCP improved considerably the capacity to visualize the gland and to detect its alterations. Additional information obtained about the pancreas from the evaluation of bile ducts with both methods was considered careful and contributed to appraise even more these explorations.

Cholangiopancreatography, Endoscopic Retrograde↗

[Gastric mucosa injuries in portal hypertension].

Portal Hypertension (PH) was diagnosed in 114/4145 patients (p) evaluated by upper gastrointestinal endoscopy during 1991-92 (2.75%). Portal hypertensive gastropathy (PHG) was found in 39.47% p. Mild PHG was observed in 82.22% and esophageal varices grade was directly correlated to PHG presence. This is a new entity to be considered because of its bleeding possibility in PH patients.

Adolescent↗

[Diagnosis of esophageal neoplasms by sponge biopsy (I)].

Fifty-one (51) patients with carcinoma of the esophagus, 27 with cancer of the gastric fundus invading gastroesophageal junction, and 28 controls with non-tumoral esophageal problems were studied by the sponge biopsy technique, an effective procedure for cytologyc diagnosis of esophageal tumors. Various advantages of this technique over esophageal washings are described and results with the sponge biopsy technique are favorably compared with them.

Biopsy↗