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Biomedical subjects

J R SCHOLTZ

Publications and source records attributed to J R SCHOLTZ.

8 recordsLinked to original sources
PubMed1965

MANAGEMENT OF ATOPIC DERMATITIS.

Fourteen patients with severe atopic dermatitis of long duration, requiring long term systemic corticosteroid therapy were managed with a treatment program designed to preserve the natural lipid surface film, avoid controllable stimuli to sweating, control skin infection, modify existing keratoderma and utilize active topical corticosteroid therapy in non-lipid vehicles. Substantial healing of the skin occurred in all cases even with discontinuance of systemic administration of steroids.

Adolescent↗
PubMed1964

MANAGEMENT OF ATOPIC DERMATITIS: A PRELIMINARY REPORT.

A treatment regimen for atopic dermatitis (disseminated neurodermatitis) which attempts to cope with the factors of dry skin and retention of sweat was successful in a series of 22 consecutive patients, all of whom remain under observation. Objectives of the treatment are: Preservation of the natural lipid surface film, avoidance of controllable stimuli to sweating, avoidance of greases and oils topically applied, control of bacterial infection in the skin, resolution of active dermatitis with topical corticosteroids in vehicles low in lipids or free of them, and correction of existing keratoderma. This program does not purport to alter atopic constitutional factors. Among the 22 patients were seven with severe dermatitis requiring prolonged, continuous or intermittent, systemic corticosteroid therapy who were treated and had no exacerbation for periods up to ten months at the time of last report. The total daily dose of topical corticosteroid is small. Systemic corticosteroid therapy was withdrawn at the initiation of this treatment and has not been reinstituted. No untoward reactions have been observed. Results to date warrant treatment and long term observation of additional patients to determine the ultimate value of this method.

Adrenal Cortex Hormones↗
PubMed1961

A new corticoid for topical therapy. Fluocinolone acetonide.

Sixty-seven patients with chronic and subacute cutaneous lesions of varying long duration that had previously been resistant to topical use of corticosteroid compounds were treated with a cream containing fluocinolone acetonide. To avoid subjective bias, only two classifications were used in appraising results: "complete clearing of treated lesions" and "not effective."Forty-eight patients had complete clearing of the treated area. Results were best in atopic dermatitis, chronic eczematous dermatitis and nummular dermatitis. Granuloma annulare, dyshidrotic dermatitis of the palms and psoriasis were not affected. In some cases in which there were multiple lesions some of the lesions were treated with fluocinolone acetonide cream and some were treated concurrently with other corticoid ointments or with noncorticoid compounds, either bland or with active ingredients. Fluocinolone was effective in more than twice as many cases as the other agents. In some of the patients with chronic disease it was possible to greatly reduce or discontinue systemic steroid therapy after fluocinolone acetonide became available. No untoward effects were observed.

Administration, Topical↗
PubMed1951

Therapeutic perspective.

Unless proper perspective is maintained in medical therapeutics, a physician in his earnest desire to cure disease may often use measures which may ultimately cause more damage than the disease being treated.In order to avoid loss of perspective, it is necessary to balance the known consequences of the disease against the expected benefits of the treatment minus the known hazards of the treatment.

Humans↗