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Biomedical subjects

J R Schenken

Publications and source records attributed to J R Schenken.

At least 19 recordsLinked to original sources
PubMed1987

Assessment of changing technologies in medicine.

Technology is the outcome of man's use of tools and reason to change the environment to his benefit. New technology creates opportunities for some and threats for others. New technology will be dramatically influenced by the political, social, economic, and ethical milieu in which it develops. An overriding concern in the near future may be cost. Cost-benefit analysis/cost-effectiveness analysis can be a helpful planning tool but should not be used exclusively to plan for technological change. Knowledge of the humanities as well as a science will be essential if we are to make the decisions needed as we approach the 21st century.

Cost-Benefit Analysis↗
PubMed1985

Plasma cell granuloma of the thyroid.

Plasma cell infiltrates in the thyroid are rare. They may represent several processes, such as localized plasmacytoma, multiple myeloma, or plasma cell granuloma (PCG). It may be difficult to distinguish these disorders on the basis of morphologic features in sections stained with hematoxylin-eosin. All may be composed of mature plasma cells, without admixed macrophages or lymphocytes, that infiltrate the thyroid and adjacent connective tissue. The identification of the uncommon, but benign, PCG is facilitated by immunohistochemical staining to demonstrate an admixture of plasma cells with cytoplasmic kappa and lambda light chains. The polyclonal nature of the plasma cell infiltrate distinguishes PCG from neoplastic plasma cell proliferation.

Female↗
PubMed1985

Cancer arising in the gastric stump. Occurrence following resection for benign peptic ulcer disease.

Two patients developed adenocarcinoma of the gastric stump 20 to 30 years following gastric resection for benign peptic ulcer disease. The bulk of the medical literature supports a small but definite increased incidence with a latency period of 20 years or more. The risk is greatest following operations that lead to greater reflux of bile and pancreatic juices into the gastric remnant. The diagnosis may be inapparent by upper gastrointestinal tract roentgenograms, and changes may not even be obvious at endoscopy. Five-year survival rates are low (2% to 4%). Because the prognosis is poor once the disease is diagnosed, the high-risk patient should be considered for intermittent endoscopic surveillance.

Adenocarcinoma↗
PubMed1981

Cystic adventitial disease.

Cystic adventitial disease represents an unusual cause of peripheral vascular insufficiency. A mucinous cyst in the outer media or adventitia progressively compromises the arterial lumen. The therapy can be either aspiration of the cyst or resection with graft interposition. We present two cases involving the popliteal artery that were treated by resection. This lesion may be recognized by its angiographic appearance associated with a lack of generalized atherosclerotic disease.

Adult↗