Nifedipine in the treatment of primary pulmonary hypertension.
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Biomedical subjects
Publications and source records attributed to J R Wise.
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A balloon-tipped catheter was used in the preoperative assessment of a patient with a solitary pulmonary arteriovenous fistula and coexistent chronic obstructive pulmonary disease and ischemic heart disease. Studies before and two months following surgical excision of the fistula showed that the increase in arterial oxygenation (49 mm Hg vs 77 mm Hg) and the reduction in the fraction of the shunted cardiac output (37% vs 6%) closely approximated the predicted preoperative estimates.
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In our experience with 98 patients, cardiac pacing has proved to be a low risk procedure with an acceptably low incidence of serious complications. Battery depletion requiring pulse generator replacement continues to be the major limitation of this technique. Placement of the pacing catheter within the coronary sinus has not been satisfactory, and measures are routinely taken to avoid this catheter position.
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