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Biomedical subjects

J R Yarnal

Publications and source records attributed to J R Yarnal.

13 recordsLinked to original sources
PubMed1982

The immotile cilia syndrome: explanation for many a clinical mystery.

With the advent of electron microscopy, ciliary abnormalities could be detected, analyzed, and correlated with clinical problems. Kartagener's syndrome, identified over 40 years ago as a triad of sinusitis, bronchiectasis, and situs inversus, was found to actually be a subset of a broader category of diseases: the immotile cilia syndrome. Two other subsets involving multiple organ systems have also been recognized.

Adolescent↗
PubMed1981

Laryngeal tuberculosis presenting as carcinoma.

A typical patient had laryngeal tuberculosis (TB) mimicking carcinoma. The accompanying patient complaints from a representative literature survey are discussed. The difficulty of clinically differentiating laryngeal carcinoma from TB or another granulomatous process is stressed, as in the utility of obtaining a simple chest roentgenogram, a TB skin test, and, when indicated, a sputum examination. The pathogenesis of laryngeal TB and the treatment of health care personnel exposed to such a patient also is mentioned. The spectrum of TB, as well as the spectrum of physicians treating TB, is changing. The presence of a laryngeal process in a patient with active pulmonary TB is an important association that must not be overlooked.

Airway Obstruction↗
PubMed1976

Rat aortic histamine synthesis during short-term hypertension.

Thoracic aortic histamine synthesis has been examined in rats rendered hypertensive for periods ranging from 1/4 to 8 days through ligation of abdominal aorta between origins of the renal arteries, in a preliminary attempt to establish whether activity of the aortic nonmast-cell histidine decarboxylase system is increased in experimental hypertension. Results indicate that aortic histamine synthesis is increased 66, 75, 96 and 55% at postsurgical intervals of 1/4, 1/2, 1 and 8 days. These data suggest at least one biochemical explanation for both increased arterial wall permeability and the arterial inflammation consistently associated with both clinical and experimental hypertension by resolving these into those associated with the prolonged inflammatory response.

Animals↗