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Biomedical subjects

J Rafalowska

Publications and source records attributed to J Rafalowska.

At least 19 recordsLinked to original sources
PubMed1988

Laminar distribution of neuritic plaques in normal aging, Alzheimer's disease and Down's syndrome.

Quantitative studies of neuritic (senile) plaques in six cortical layers were carried out in brains from people with confirmed clinical and neuropathological diagnosis of senile dementia of the Alzheimer type (SDAT) and Down's syndrome (DS). The same studies were performed on brains of normal old-aged people. In Alzheimer disease (AD) and DS cases the highest numbers of neuritic plaques (NP) were observed in temporal lobe layers III and II and occipital lobe layers III, IV and II. In normal old-aged people the highest numbers of NP were found in temporal lobe III and V and in occipital lobe IV, III, and V layer. The plaque numbers in both temporal and occipital cortices of AD and DS were significantly higher than that of normal old-aged people but there was no difference between AD and DS.

Aged↗
PubMedDate not supplied

[Usefulness of volumetric studies in the evaluation of respiratory efficiency in nervous system diseases].

In nervous system diseases impairing the efficiency of respiratory muscles the authors determined vital capacity, minute ventilation and respiratory capacity. On the basis of volumetric investigations the authors tried to find an optimal schedule for administration of drugs in myasthenia and determine the usefulness of volumetric and gasometric measurements for the evaluation of respiratory efficiency in neurological diseases.

Body Weight↗
PubMedDate not supplied

[Complications arising from the use of controlled respiration in patients with neurological diseases].

The authors applied controlled respiration in 112 cases of central nervous system diseases, polyneuropathies and myasthenia. During clinical observation or on autopsy in 30 cases complications were found in the form of subcutaneous and mediastinal emphysema or pneumothorax, narrowing or chondromalacis of the trachea, granuloma formation, decubitus ulcers in the trachea with or without bleeding, and haemorrhagic-ulcerative tracheitis. In 7 cases (6.25%) these complications caused death. Factors leading to complications and their prevention are discussed.

Adolescent↗
PubMedDate not supplied

On pure motor hemiplegia (Fisher's syndrome).

The authors described three cases of so-called "lacunar strokes" with pure motor hemiplegia. Clinical diagnosis in all three cases was middle cerebral artery thrombosis. In cases 1 and 2 small post-malacic lacunes were found in the basal part of the pons. In case 3 the lesion was located in the pyramidal tract within the pons and medulla. In all cases advanced arteriosclerotic changes were observed. "Lacunar stroke" can result from a lesion of both the pons and the medulla. The clinical syndrome may be engendered also by selective lesion of the pyramidal tract.

Aged↗