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J Rakoski

Publications and source records attributed to J Rakoski.

15 recordsLinked to original sources
PubMed1991

Clinical characteristics of patients with repeated systemic reactions during specific immunotherapy with hymenoptera venoms. A retrospective study.

In general, specific immunotherapy with hymenoptera venoms can be considered as safe, but occasionally there are patients who cannot reach the maintenance dose due to repeated systemic reactions (RSR) or who suffer from RSR during maintenance therapy. In a multicenter retrospective study comprising seven departments in Germany, Austria and Switzerland 23 patients with RSR were reported from approximately 3000 patients treated with hymenoptera venoms (bee and wasp venom to approximately equivalent frequency). From these, 22 were allergic to bee venom and only one to vespid venom. In general the clinical symptoms of RSR were milder than the initial reaction. But 4/23 (18%) exhibited cardiovascular reactions up to full shock. Neither anamnestic details, reactivity in skin tests or in vitro tests revealed a special pattern of patients with RSR. In some patients, however, an extremely high reactivity in the skin test was found and may indicate the possibility of further RSR.

Adolescent↗
PubMed1991

Patch testing with amalgam at various concentrations.

27 patients with positive D3 reactions on patch testing to 3 mercury screening allergens were patch tested with 13 mercury patch test preparations, 6 inorganic and 7 organic, and amalgam 20% pet. The 13 patients (all women) showing positive reactions to 20% amalgam were then patch tested to reducing concentrations. 2 patients reacted down to 1%, 4 down to 2%, 4 down to 5%, 2 down to 10% and 1 only to 20%, a total of 10 of the 13 patients therefore reacting to the 5% concentration of amalgam. The appropriate patch test concentration of amalgam is discussed and the clinical significance and female preponderance of amalgam reactivity suggested as being worthy of further investigation.

Adolescent↗
PubMed1989

[Type I allergy to rubber gloves containing latex].

We report on a 23-year-old female patient showing anaphylactoid mucosal reactions when handling Latex rubber gloves. Usually, type I intolerance against rubber gloves is due to allergy against Latex mediated by IgE. In addition, we discuss some general allergologic problems regarding the handling of rubber gloves.

Adult↗
PubMed1989

[The significance of dermatologic management in computer-assisted occupational dermatology consultation].

At our occupational outpatient clinic, 230 patients were treated for about 15 months. With the help of a standardized questionary, we registered all the data regarding the relevant substances the patients contacted during their work as well as their various jobs since they left school. The patients were repeatedly seen and trained in procedures of skin care and skin protection. If required, we took steps to find new jobs for them within their employing company; this was done in cooperation with the trade cooperative association according to the dermatological insurance consultanship. If these proceedings did not work out, the patient had to change his profession altogether. All data were computerized. As an example for this computer-based documentation we present the data of barbers.

Adult↗
PubMed1988

[Reproducibility of epicutaneous test results].

857 non-dermatologic patients were patch-tested with the Finn-Chamber-technique. The sequent testings under identical conditions were made after 3-12 months. Readings were done after 24, 72, 96 hours and later. During the first test-series we found 44 reactions to be positive, 20 remained identical during repetition-testings, 7 became negative and 36 positive reactions appeared. So reproducibility was 46% for the positive results of the first testing serie.

Allergens↗
PubMed1988

[Risks of specific hyposensitization treatment].

In appropriate cases of diseases mediated by IgE, specific hyposensitization may be a successful way of treatment. According to prospective studies, the risk of side effects ranges between 0.1 and 1% per injection. We report on cases with fatal outcome and suggest suitable strategies in order to avoid serious complications.

Anaphylaxis↗
PubMed1988

[Hyposensitization with cross-reacting pollen allergens].

Grass-pollen are one of the most common allergens in pollinosis. Rye-pollen are the most important allergens among cereals-pollen in Germany. Between pollen-allergens, the phenomenon of cross-sensitivity is well-known. In the RAST und RAST-Inhibitionstest the cross-sensitivity between grass-pollen and rye-pollen is well documentated. In the clinic the test and challenge with some grass-pollen ist suitable for the diagnosis and planing of therapy. Therefore, it seems, that therapy with grass-pollen should produce the same results as a treatment with grass- and rye-pollen. We treated 35 patients allergic with poaceae-pollen for 3 years in two different ways: One group we treated only with grass-pollen, the other group we treated with grass- and rye-pollen. Under the therapy we controlled the specific IgE and IgG, the nasal challenge-test and the subjective symptoms by diaries and questionnaires. The specific IgE for phleum pratense and rye-pollen decreased, the specific IgG increased in both groups. There were no differences between the two therapy-groups. In the clinical data-subjective and nasal challenge-the therapeutic effect seemed to be better in the group treated with grass- and rye-pollen.

Adult↗
PubMed1985

[Frequent occurrence of dyshidrosis-type eczemas of the hand caused by oil-in-water emulsion in metalworkers].

In a metal working enterprise, about 1/3 of the workers who had come into contact with a certain cutting solution, fell ill with an eczema of the hand in short time, the clinical aspect of which reminded a dyshidrosiform eczema of the hand. An epicutaneous test made with the emulsion oil-in-water had a negative result. After the cutting solution had been replaced by another product, the hand lesions disappeared rapidly. In the literature, we could not find any informations concerning dyshidrosiform eczemas of the hand, while manipulating emulsions oil-in-water. However, a tendency to sudation of the hands is known.

Adult↗
PubMed1977

[Pre-seasonal treatment of hayfever with a pollen depot extract (author's transl)].

90 patients with "hayfever" - that means pollenallergic diseases of the respiration tract and the eyes - were treated in spring 1974 and 1975 with a tyrosinabsorbed grass and rye depot extract with three injections before the pollen-season. Only 16 patients had an isolated grass-rye-pollen-allergy in skin test, all the other patients had additional extrinsic allergies. These results were proved by RAST. One third of the patients had bad side-effects (27 out of 90) during the treatment. 17 patients showed general reactions and ten patients very strong local reactions. We think that these side-effects were caused by contact with antigens (hairs of animals, foods, flowers of trees) during therapy and acute or chronic infections. The results of therapy were asked by a questionnaire one year after the series of injections, there were 37 improved, 32 unchanged and/or worsened in pollen-season after treatment. Nevertheless the results encouraged to continue this treatment with the grass-rye-pollen-extract. It could be used as an "initial treatment" in pollinosis patients with a wide spread allergy just before the beginning of the pollen-season. It is necessary to fullfill all procedures of precaution which are in use in hyposensitizationtherapy to prevent stronger side-effects.

Adult↗
PubMedDate not supplied

[Special dermatologic problems of clean-room work].

Since the development and production of microelectronic processes require so-called "clean-room" conditions, dermatologists increasingly are confronted with the skin problems of persons working within this environment. The skin problems associated with dryness are obviously attributable to a low humidity in the "clean-rooms", as additionally factor caused by the lamellar air flow of filtered air.

Electronics↗