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Biomedical subjects

J Ranft

Publications and source records attributed to J Ranft.

At least 19 recordsLinked to original sources

Duplex sonography of venous atheromatosis found in the venous part of hemodialysis fistula.

Manifestation of atherosclerosis is one of the alterations in venous bypass grafts. Its progression and morphology usually cannot be described by sonography. The venous part of a hemodialysis fistula can be compared to a venous bypass graft. The authors investigated the venous part of hemodialysis fistula in 16 patients. They found atherosclerosis in 7 patients. The morphologic findings were similar to arterial atherosclerosis. Looking at the venous part of hemodialysis fistulas may be an adequate model to investigate the initiation and progression of atherosclerotic lesions in venous bypass grafts.

Adult↗

[Reactive hyperemia after arterial occlusion: comparison of infrared telethermography and laser Doppler flowmetry].

Before, during and after arterial occlusion we measured Laser-Doppler Flux (LDF) and skin temperature using Infrared-Thermographie (IRT) in 40 healthy adults (20 female, 20 male). In the region of the hypothenar eminence of the left hand LDF and skin temperature showed significantly higher values in male compared with female subjects prior to occlusion (p < 0.01 resp. p < 0.05). After arterial occlusion for 120 seconds LDF showed a significant overshoot of 71.3% (+/- 39.5%) above baseline. During this phase of hyperemia skin temperature rose from 33.5 to 34.8 degrees C (p < 0.0001). This reaction was similar in men and in women. Changes in skin temperature were slower and more prolonged compared with the rapid changes of LDF. The absolute temperatures were significantly higher when we used IRT compared with temperatures measured by resistance thermometry. Both methods showed a close correlation (p < 0.0001, r = 0.891). Using the IRT technique a large number of skin temperatures can be measured simultaneously and temperature changes can be detected and visualized by colour thermograms. Postocclusive cutaneous hyperemia induces similar responses in LDF parameters and in skin temperatures. IRT therefore could be used as an additional tool for the assessment of physiological and pathological functions of the cutaneous microcirculation.

Adolescent↗

[Location and morphology of plaque of the carotid artery and femoral artery in the B-scan image in employees of the Düsseldorf public officials: value of screening study].

With the help of high-resolution real-time sonography, we examined the carotid and femoral arteries in 3,500 asymptomatic persons to assess early states of atherosclerosis an to prove the utility of B-Scan-Sonography in this aim. We found 384 people having plaques, totally 769 pl. 68 p.c. of all plaques we were found in the femoral arteries, 32 p.c. in the carotid arteries, in each case with preference of the bifurcation and the pre-bifurcation-region. This seems to confirm earlier studies on this theme. As regards to the morphology, we found 67 p.c. (of all plaques) being faintly-echogenic ("fatty-streaks" or intermediär type). 73 p.c. of all plaques showed a smooth or faintly irregular surface-character. More than 75% of all plaques had a volume less than 0.3 ccm. Altogether, the results verify the assessment of mostly early states of atherosclerosis with the help of real-time-ultrasound and underline this method being a good and sufficient non-invasive-technique for screening-examinations on an asymptomatic collective.

Arterial Occlusive Diseases↗

[Arteriosclerosis vascular changes as an expression of the local effect of mechanical continuous stress--observations of the femoral artery of marathon runners].

The arteries of the thigh of 126 male marathon runners at the age of 41.6 +/- 11.3 years were examined with B-Scan-ultrasound. 32 (62.1%) persons were found with arteriosclerotical plaques. All of them were older than 35 years, so the number of arteriosclerosis in this group increases to 36.4 percent (n = 88). 38 persons were younger than 35 years. Persons with plaques started training about 10.9 years later than those without plaques. Correlations of plaques and age, age of starting training, years of training and km/year were found. The numbers of riskfactors showed significant differences between both groups but the correlation of "having no risk factor" and arteriosclerotical plaques was higher than the correlations of nicotine, hypertension, hypercholesterolemia and plaques. It seems that marathon running itself is a risk factor of developing arteriosclerotical plaques in the femoral arteries particularly if the age of starting training is higher than 30 years.

Adult↗

[Prevention of arterial and venous vascular diseases, especially the correlation between risk factors and arteriosclerosis].

In a epidemiological study 3840 clerks of state of North Rhein Westfalia were investigated concerning the frequency of atherosklerotic leasions of the carotid and femoral arteries in duplex scanning. 17% of all investigated showed independency to age, sex and risk factors alterations of the vessel walls. Men had twice as much plaques as women and male subjects with multiple risk factors had four times more plaques than those without.

Adult↗

[Imaging real-time sonography (B-scan) of peripheral veins--possibilities for use with reference to secondary prevention].

In 2400 male and 1400 female persons the proximal femoral and saphenal venous vessels have been monitored and measured with a Ultramark 4, build by ATL, by use of 7.5 megacycle/s. transducer. Moreover, we took the venous calibers at the junction of the saphenous veins into femoral veins. In patients with marked varices or less symptomatic patients as well as clinically asymptomatic persons with positive family history there could be found significantly bigger dilatation of vessel calibers in those patients laying than those standing up, in contrast to healthy persons. B-Scan ultrasound consequently in future offers a new range of diagnostic values in examination of venous vessels, that is to say a non-invasive, reproducible and haemodynamically tolerable method which helps to improve secondary prevention.

Female↗