Glutamate solutions of either 50 mM applied on the membranous labyrinth or 1 mM perfused into the lateral canal in cats increased spontaneous and stimulus-evoked activity of vestibular neurons. Kainic acid (10(-4) M) perfused into the labyrinth produced a depolarizing action on vestibular afferents. These results indicate that glutamate could be an excitatory neurotransmitter at the synapse between vestibular hair cells and afferent nerve fibers in the cat.

Action Potentials↗

PubMedDate not supplied

Cancer chemotherapy administered via hemodialysis fistulas.

End-stage renal failure (ESRF) patients can develop cancer before or after kidney disease occurs. Cancer chemotherapy often needs to be administered via the sort of central venous catheter that is normally avoided in ESRF care. Three cases are presented in which ESRF patients received chemotherapy for cancer via existing hemodialysis fistulas, and the consequences of central venous access in a fourth patient are discussed.

Journal Article↗

PubMedDate not supplied

Efferent innervation of vestibular receptors in the cat: a radioautographic visualization.

A tritiated amino acid tracing method was used to test the hypothesis that a unilateral group of vestibular efferent neurons of the brain stem may present different innervation patterns to the sensory vestibular epithelia of the ipsi- and contralateral labyrinths. Densitometric analysis of labeled efferent endings suggested a heterogeneity of the efferent projections issuing from a unilateral predominated in the maculae utriculi and cristae ampullares of the semicircular canals. These findings are discussed as a function of other data related to efferent vestibular control.

Animals↗

PubMedDate not supplied

Your child--first steps. The world of the senses.

Explore the source record for details and available documents.

Brain↗

PubMedDate not supplied

Your child--first steps. Kids, start your engines.

Explore the source record for details and available documents.

Brain↗