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Biomedical subjects

J Reeve

Publications and source records attributed to J Reeve.

250 records · Page 14Linked to original sources
PubMed1973

A case of chronic granulocytopenia associated with vasculitis and amyloidosis.

A patient is described with chronic neutropenia who was followed for 22 years. She had varying patterns of neutropenia, sometimes cyclical, sometimes almost agranulocytic; at times the counts were normal. The course was complicated by a vasculitis and finally by large vessel thrombosis; extensive amyloid was found in small vessels at necropsy.

Adolescent↗
PubMedDate not supplied

Triglyceride-lowering effect of marine polyunsaturates in patients with hypertriglyceridemia.

Twenty male patients with primary hypertriglyceridemia were treated for 4 weeks with daily supplements (15 g) of oil, which provided approximately 6 g of polyunsaturated fatty acid (PUFA) either of fish or of vegetable origin. Total plasma cholesterol concentrations were unaffected, but both types of supplement increased high density lipoprotein-3 (HDL3) cholesterol concentrations. The fish, but not the vegetable, oil supplement led to a decrease in plasma triglyceride concentrations. Very low density lipoprotein (VLDL), fatty acid composition, and VLDL triglyceride kinetics were subsequently studied in five patients (four male, one female) before and after 4 weeks of therapy with 15 g of the same fish oil. The fish oil led to increases in the proportion of eicosapentaenoic acid in both the VLDL triglyceride and phospholipid fractions, but the increase was greater in the latter. In contrast, the proportion of docosahexanoic acid was increased only in the VLDL triglycerides. The decrease in plasma triglyceride concentrations that occurred with fish-oil therapy was accompanied by a reduction in the absolute catabolic rate of VLDL triglyceride, implying a concomitant change in synthetic rate; the fractional catabolic rate of VLDL triglyceride was unaltered. It is suggested that polyunsaturated fatty acids of marine origin may be therapeutically useful for hypertriglyceridemia.

Adult↗
PubMedDate not supplied

Attitudes about cancer and knowledge of cancer prevention among junior high students in Calgary, Alberta.

Results from a survey of junior high students conducted in preparation of curriculum materials on cancer prevention are reported. Students in the survey (n = 246) consider cancer to be a serious disease, not particularly amenable to treatment, and caused by many things. About half the students mentioned avoiding tobacco use as important in preventing cancer. However, 27% were unable to identify any ways to avoid getting cancer. Specific knowledge of dietary practices recommended to reduce cancer risk was poor, with fewer than 10% of students mentioning high fibre or low fat as important dietary habits. Knowledge of factors related to skin cancer was better, with 53% of students mentioning avoiding sun exposure as a way to reduce the risk of skin cancer. The majority of students (71%) wanted more information about cancer. The results from the survey indicate a need for cancer-prevention materials in the school curriculum.

Adolescent↗
PubMedDate not supplied

Spinal and somatic growth in patients with juvenile chronic arthritis treated for up to 2 years with deflazacort.

We previously reported a double-blind controlled trial of Deflazacort vs Prednisone in patients with Juvenile Chronic Arthritis who had required corticosteroid therapy for at least one year. This paper presents further results on an additional 11 patients, making 26 altogether, who were treated for one year with deflazacort. Fourteen of these went on to a second year of deflazacort treatment. As previously reported, the relative rate of spinal bone mineral growth in the first year was greater for the spinal bone mineral content than for the body surface by about 70%. In the second year of treatment spinal bone mineral continued, with wide variations, to grow at the same or a very slightly greater rate. However, somatic growth recovered so that there was no significant difference between the relative growth rates in the spinal bone mineral and the body surface area in year 2 (P = 0.78). Deflazacort therapy appears to permit appropriate growth of the spine in relation to the rest of the body against a background of variable growth impairment due to the disease process and the treatment required to control it.

Anti-Inflammatory Agents↗
PubMedDate not supplied

Nurses' attitudes towards health care assistants.

This descriptive study aims to evaluate trained nurses' knowledge base and attitudes towards the introduction of HCAs, as a basis for future programmes of training, and the formulation of policies. The possibility of a relationship between the demographic variables of the subjects and the knowledge base and the attitudes of the nurses is also examined. A questionnaire was sent to trained nurses working in specific ward areas at two hospitals in the Plymouth Health Authority, Devon. The results indicated that heterogeneous nature of the group and illustrated that nurses have a poor knowledge of HCA issues, with more respondents giving incorrect responses than correct ones. However, responses showed generally that attitudes towards the introduction of HCAs were positive.

Allied Health Personnel↗