Biomedical subjects

J Reinosa

Publications and source records attributed to J Reinosa.

5 recordsLinked to original sources

PubMed1996

Halothane anesthesia and serum electrolytes.

The disparate observations on the effect of halothane anesthesia on the serum electrolyte levels in humans prompted us to carry out this work. In this study the levels of sodium, potassium, magnesium, calcium, chloride and inorganic phosphorus were determined in serum of 25 male and 15 female patients, with an age range of 15 to 40 years, who had various pathologies requiring surgery and who were given halothane anesthesia. Significant difference were detected in the concentrations of sodium, potassium, calcium and inorganic phosphorus between presurgical and post-anesthesia induction samples. The truly striking finding in the present study was the significant increase in serum inorganic phosphorus in the intra-operative period. It is suspected that this increase is due to a defect in phosphorylating mechanisms which leads to a rapid hydrolysis of stored and preformed ATP.

Adolescent↗

PubMed1996

Effect of isofluorane anesthesia on serum levels of Zn, Cu, Fe, Mn and Co in humans.

In this study the levels of zinc, copper, iron, manganese and cobalt were determined in serum of 25 male and 15 female patients, aged 18 to 35 years, with various pathologies requiring surgery, and who had received isofluorane anesthesia. Significant differences were detected in the concentration of zinc, copper, iron and manganese between presurgical and post-anesthesia samples. The truly striking finding in the present study was the significant increase in serum Zn in the post-operative period. The fact that alterations in the serum levels of these elements occurred only after a considerable time had elapsed following the intervention (24 hours), leads to the conclusion that the changes in serum cation concentration very likely result from surgical trauma and not from isofluorane anesthesia per se.

Adolescent↗

PubMed1996

[Changes in liver and kidney phosphorus in guinea pigs exposed to high doses of vitamin A (retinol)].

In this study, the serum, urinary, hepatic and renal levels of total inorganic phosphorus (Pi) were determined in guinea pigs treated with 100,000 U.I. of vitamin A, dissolved in Tween Span, given each day by intramuscular injections during seven days (treated group), and compared with the levels in healthy guinea pigs which were given the same feed as the treated group, and received the same amount of Tween Span (control group). The activity of the enzymes alkaline phosphatase and acid phosphatase was simultaneously determined in liver and kidneys of both groups, and the phospholipid content in serum and tissue was also determined. The treated group did not show changes in serum and urinary phosphorus as compared with the control group. Liver and kidney of the treated group showed an increase in total Pi (p < 0.05). In this group a definite increase (p < 0.05) was also observed both in serum and tissue levels of phospholipids, as well as in the activity of the liver and kidney enzymes studied. These results suggest that phosphorus enters the blood stream in the form of lipid complexes (phospholipids) that are involved in certain characteristic functions.

Animals↗

PubMed1989

Changes in copper, zinc and iron content in serum and saliva in various otorhinolaryngological ailments.

Copper, zinc and iron concentrations were determined in blood serum and parotid saliva of patients with various otorhinolaryngological disorders such as sinusitis, rhinitis, otitis and amygdalitis. Comparing results between individuals of control group and patients significant differences were observed in concentrations of the metals studied as a result of the different infections diseases.

Adult↗

PubMed1988

Concentration changes of zinc, copper and iron in serum of chronic chagasic myocardiopathic patients.

Zinc, iron and copper content in serum of 75 myocardiopathic chagasic patients together with that in 29 healthy controls were determined. Blood samples were taken by catheterization from the superior cava vein, coronary sinus, pulmonary artery and a peripheral artery, usually the femoral. In general, serum zinc and iron levels tend to diminish in chagasic patients, while serum copper levels tend to increase. The coronary, systemic and peripheric gradients indicate that all these metal elements tend to deposit in heart tissue. Although zinc and iron tend to be deposited also in liver and other tissues, copper is released from them into the blood stream. Further studies should determine the requirement of these metal species in heart and other tissues of experimental animals in order to obtain more conclusive information about the cause of the serum metal impairment observed here.

Adult↗