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J Rey Calero

Publications and source records attributed to J Rey Calero.

27 records · Page 2Linked to original sources
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[The immunogenicity of the vaccine against the HBV in the mentally retarded].

Our group carried out during 1989 a serological cross sectional study in 1,024 mentally handicapped patients (231 with Down's syndrome [DS] and 793 affected with other mental disturbances [OMD]), educated in seven institutions of the Madrid region. Those patients with negative HBsAg and anti-HBc markers were considered vaccination susceptible individuals. This group was constituted by 546 individuals. The regime of vaccination used was 0-1-6 m, and the dose, 20 micrograms i.m. The present study makes an evaluation of the postvaccine serologic results one month after the third dose. It was considered the age, sex and if he or she suffers from Down's syndrome or not. Corresponding with these variables the seroconversion rate (percentage of patients with greater than or equal to 10 IU/l of anti-HBs) was determined as well as the geometric mean titer (GMT) of antibodies. The seroconversion rate was 97.1% in the group affected with DS and 95.5% in the group with OMD, not being this difference statistically significant. There is not also significant association with regard to the sex, being the seroconversion rate in males (94.7%) and females (97.6%) very similar. However, it is significant difference between the mean age of the "responders" to the vaccine (24.6 years of age) and that of the "non responders" (33.3 years of age) (p less than 0.001). Thus, the age exerts a negative influence in the response to the vaccination. The titer of anti-HBs antibody, expressed using the GMT, has significant association with the sex (p less than 0.001) but not with the type of mental disturbance.(ABSTRACT TRUNCATED AT 250 WORDS)

Aging↗
PubMedDate not supplied

[Epidemiological study of fertility in adolescents in the Autonomous Community of Madrid].

OBJECTIVE: The purpose of this study was to research the frequency and distribution of fertility in adolescence and, in looking at different environments within the Autonomous Community of Madrid (ACM), to evaluate the relationship of fertility rates to determined variables of a socio-economic, educational and demographic nature. DESIGN: An observational crossover study was carried out. SETTING: Autonomous Community of Madrid. PATIENTS AND OTHERS PARTICIPANTS: In this study, the specific rate of fertility in adolescents (SRFA) was calculated and the correlation between the SRFA and variables of a socioeconomic, educational and demographic nature were analysed by means of the multiple linear regression method. MEASUREMENTS AND MAIN RESULTS: We found important differences in the distribution of fertility within the ACM. There was also a positive correlation (p < 0.05) between the SRFA and those variables which expressed the percentages of illiteracy, industrial workers and with the synthetic youth index. A negative correlation (p < 0.05) was found for the percentages of graduates, professionals and technicians, managers and directors and with the synthetic ageing index. We found no correlation with the unemployment index. On applying the multivariant model, the variable that weighed most on fertility was the level of education, which was in our case measured by the percentage of illiteracy. CONCLUSIONS: We found an uneven spread of adolescents' fertility rates in the Autonomous Community of Madrid. The fertility rates were higher in those boroughs where there was more illiteracy.

Adolescent↗