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Biomedical subjects

J Reznícek

Publications and source records attributed to J Reznícek.

At least 19 recordsLinked to original sources

[Urinary oxalic acid excretion in chronic kidney failure and after kidney transplantation].

Urinary oxalic acid excretion was examined in 61 patients with chronic nephropathies and in 21 patients after renal transplantation with a varying mean glomerular filtration. In both groups of patients a correlation was found between the plasma oxalic acid and serum creatinine and by a hyperbolic correlation between plasma oxalic acid and creatinine clearance. Moreover the authors found a direct correlation between oxalic acid and FEoxalic acid and FE(Na)+, FEH20 and FE1-ascorbic acid in both patient groups. Various chronic nephropathies and treatment in both groups did not affect the revealed correlations. In 13 healthy subjects during the period of maximum water diuresis urinary Na+ excretion did not increase but there was a significant increase of the l-ascorbic acid and oxalic acid excretion. In a group of 8 patients in the polyuric stage of chronic renal failure without dialysis treatment under conditions of increased dietary NaCl intake (15 g/24 h) a significant increase of the urinary Na+ excretion was recorded while the l-ascorbic acid and oxalic acid excretion was unaltered. From the assembled values of the examined biochemical indicators ensues that urinary oxalic acid excretion, similarly as ascorbic acid excretion, depended on water excretion.

Adult

[Erectile dysfunctions in patients treated with hemodialysis and kidney transplantation].

The incidence of erectile dysfunction in patients suffering from severe renal diseases in the stage of renal insufficiency is significantly higher in comparison with healthy men of the same age. In the etiopathogenesis of erectile disorders, both organic and psychogenic factors participate in combination. By means of a questionnaire, the authors have collected information from 53 men treated by hemodialysis and kidney transplantation because of renal failure. Erectile disorders occurred in 41.5 per cent of men with chronic renal insufficiency. On one side hemodialysis improved the erectile dysfunction in two patients, in total, however, the incidence of impotence increased to 64.2 per cent. Erectile dysfunction was reported by 71.7 per cent of patients after kidney transplantation. The authors describe two cases of iatrogenic arterial insufficiency of the penis as the cause of impotence after secondary renal transplantation. In uremic patients as possible therapeutic methods, intracavernous application of vasoactive drugs or penile prostheses implantation should be considered. (Fig. 2, Ref. 20).

Adult

[Vitamin B12 and folic acid in chronic kidney failure and after kidney transplantation].

Vitamin B12 in plasma, folic acid in plasma and erythrocytes were examined in 11 patients in the polyuric stage of chronic renal failure without dialyzation treatment, in 38 patients included in a long-term dialyzation programme before and after 3 months' oral administration of folic acid--(2 X 5 mg week)--and in 23 patients after transplantation of the kidneys. In none of the examined groups vitamin B12) and folic acid deficiency in plasma was detected. A reduced folic acid level in erythrocytes, but still in the reference range, was found in patients in the long-term dialyzation programme without supplementation. Supplementation with folic acid increased its concentration in plasma 4.5 times and in red cells 5.5 times. Haemodialysis did not influence the concentration of the examined indicators in plasma and red cells. According to the recorded results it is not necessary to supplement patients in long-term dialyzation programme and after renal transplantation with vitamin B12 and folic acid, if their dietary protein intake is not restricted.

Female

[Transurethral invaginating ureterectomy].

The principle of transurethral invagination ureterectomy is in the invagination of the stump of the ureter its retraction into the urinary bladder and resection of the levels of the mucosa of the urinary bladder. The authors describe the surgical procedure and experience with the treatment of seven patients.

Aged

[Antegrade pyeloureterography in the transplanted kidney].

Antegrade pyeloureterography performed via fine puncture needle yields detailed imaging of the anatomy of the renal pelvis, calices, and ureter of the transplanted kidney. It is a simple and safe examination method providing information which, as a rule, can not be obtained by urography, radioisotope gammagraphy or ultrasonography. Puncture of the collecting system of the transplanted kidney with subsequent pyeloureterography is indicated for determining the site and nature of the obstruction in the ureter in urinary stasis in the transplanted kidney, for diagnosing urinary fistulas, for functional examination of the dilated upper urinary tract, as well as for percutaneous treatment of urological complications after kidney transplantation.

Humans

Dynamics of serum minerals changes after renal transplantation.

In 27 patients surviving with transplanted cadaver kidneys for 12-107 months, calcium, phosphorus, magnesium and creatinine serum levels, glomerular filtration rate and incidence of serum mineral levels pathological deviations following renal transplantation were evaluated. In early posttransplantation period hypercalcemia and hypomagnesemia developed in one fourth of the observed group of patients and hypophosphatemia in two thirds of patients. Expressive hypermagnesemia developed in one patient. Calcium and phosphorus levels gradually normalized, excluding rare exceptions; magnesium serum level exceeded an upper limit of normal values in majority of patients, nor to medicamentous treatment was stated.

Adult

Transplantation of pediatric kidneys into adult patients.

The authors are dealing with the problems of transplantation of pediatric kidneys into adult recipients. Kidneys obtained from children who died 1-3 year old can be both transplanted into one adult recipient. The authors used this method in transplantation of kidneys from 2 - year old donor into adult recipient.

Adult

Operations in patients treated by regular haemodialysis.

Patients with chronic renal insufficiency treated by regular dialysis tolerate well surgical interventions provided they are appropriately prepared for the operation. It is first of all the management of symptoms of the uraemic syndrome by an effective dialysis, the follow-up during the operation and in the immediate postoperative period. On the basis of experience with 31 regularly dialysed patients, the authors have set their criteria for a total anaesthesia. Also the risks and the most frequent complications occurring during and after the operation are pointed out.

Adolescent

The ureter in renal transplantation.

The outcome of kidney transplantation depends on several factors. The quality of the ureter of the transplanted kidney and the technique of its connection with the recipient's urinary tract seem to be two of the most important ones. In this paper the authors analyse the incidence of ureteral complications of the grafted kidney in 99 ureterocystoneostomies performed in conjunction with kidney transplantation. Urinary fistulas occurred in 7, stenosis of the ureter in 3 cases. The diagnostic possibilities and treatment of the complications are discussed.

Constriction, Pathologic