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Biomedical subjects

J Rico Irles

Publications and source records attributed to J Rico Irles.

At least 19 recordsLinked to original sources
PubMed1995

[Pleuropericarditis as the only manifestation of Legionella pneumophila infection].

Pleural effusion caused by Legionella is seen fairly frequently but is hardly ever of great clinical significance. Pericardial involvement has been described only rarely. We present a case of pleuropericarditis as the only sign of infection by Legionella pneumophila in a 66-years-old man with no prior history of disease. The patient came to the hospital with chest pain suggestive of pleurisy, low-grade fever, dry cough and dyspnea. The etiology was not suspected and the diagnosis was made retrospectively based on indirect immunofluorescence. After 3 weeks of treatment with high dose of erythromycin the patient recovered and remains asymptomatic to date. We conclude that infection by Legionella pneumophila should be suspected in patients with pleurisy or pericarditis of unknown cause.

Acute Disease↗
PubMed1994

[A retrospective study of alcoholism at the Hospital Universitario de Granada (1): the sociodemographic and clinical characteristics].

This work offers the results of a retrospective study carried out on 856 patients diagnosed as suffering from alcoholism and/or other alcohol-related illnesses over 120456 who were admitted at the Granada University Hospital over the period 1985-1990. The patients have been classified in a distribution according to various factors, including age, sex, place of residence, profession and hospital admittance and discharge procedure. We have also taken into account both annual and accumulated incidence, as well as the distribution of those patients in the different hospital services and the evolution of the global average hospital stay. We then offer a study contrasting our results with other national and international studies, taking into account elements such as conceptual diversity and similarities and differences in methodology.

Adolescent↗
PubMed1994

[Lyme disease: a multisystemic condition].

While Lyme's Disease is clinically well known since 1920, its complete ascertainment and its etiological agent, as well as the details of its transmission mechanisms and multisystemic clinical manifestations (mainly dermatological, cardiac, neurological and articular) have been only recently known. In Spain, the number of papers published on this affection has increased lately, although its understanding is still not as generalized as it should be. This review focuses mainly on our country's experience, as well as on its clinical characteristics. We think that it is a very important affection, since its estimated incidence is 500 cases per year, a significant figure compared to other European countries.

Humans↗
PubMed1991

[Derivatives of pro-opiomelanocortin (ACTH and beta-endorphin) in chronic alcoholics].

The plasmatic concentration of beta-endorphins and ACTH were measured in 31 alcoholic patients and in a control group (N = 16), to test the possible relation between chronic alcohol intake and propiomelanocortin production. There were found a decrease of beta-endorphins plasmatic levels in chronic alcoholic group, apart of clinical manifestations or abstinence period (one month maximum). This decrease can be cause by the chronic alcohol intake, and can be mediated by the tetrahydroisoquinolines (TIQs) or otherwise be the cause and not the consequence of alcoholism. The global plasmatic levels of ACTH were decreased but it was significant in the subgroup of alcoholics with liver disfunction, mental illness and those who carry on drinking.

Adrenocorticotropic Hormone↗
PubMed1991

[Evaluation of nutritional status in patients admitted to an internal medicine department. Study of 100 cases].

We have confirmed that malnutrition is very frequent in hospitalized patients. There is no agreement about which are the indexes or criteria agreement about which are the indexes or criteria that can be used to define malnutrition, specially in early stages. In the present work, we have studied 100 patients randomly chosen amongst the admissions that occurred in the Internal Medicine Department over a period of one year. The patients were submitted to a protocol which included the following: anthropometric measurements, seric proteins and routine determinations (sugar level, cholesterol, uric acid, etc.) It has been considered as malnourished those patients who presented some marker with a value lower than 90% of the standard value. According to these criteria, 25 of them had a caloric-protein malnutrition, 24 had a proteic malnutrition and 25 of them had mixed malnutrition. The most sensible parameters had been the triceps skin fold and retinal transporting protein.

Adolescent↗
PubMed1991

[Hematological, biochemical and electroneurophysiological changes in asymptomatic drinkers: a sensitivity study].

An electro-neuro-physiological, biochemical and hematological study was carried out in 3 groups of non-symptomatic drinkers: those in group A had a daily alcohol intake of less than 40 grams of alcohol; group B had a daily intake of between 40 and 80 grams of alcohol and those in group C had an intake greater than 80 grams of alcohol per day. The aim of this study was to demonstrate that all the parameters evaluated show quicker alterations when the intake of ethanol is chronic. Electroneuro-physiological parameters were less sensitive than the following indexes: VCM, GGT, GOT, GPT. However, in 50.9% of the patients there were changes in conduction speed, which is an important point to take into account when making a therapeutic decision.

Adult↗
PubMed1990

[The neurophysiological study of diabetic polyneuritis. Apropos 100 cases].

Alterations in nervous transmission might be an early feature of diabetic peripheral polyneuropathy, even in the subclinical stage. We performed a study on 100 diabetic patients. Those with possible endogenous or exogenous causes of neuropathy were not included. We studied the motor distal latency of right peroneal and cubital nerve and the sensory distal latency of median nerve by the use of electromyogram. The neuropathy incidence was 34.3%. One of the results was that conduction in males was slower than in the female control group; this disappeared in diabetic patients.

Adult↗
PubMed1990

[Dehydroepiandrosterone sulfate, cortisol and their precursors in severely ill (acute and chronic) patients].

This study tries to evaluate the interrelationship amongst certain corticoadrenal hormones (Dehydroepiandrosterones-Sulphate (DHEA-S), progesterone, 17-OH progesterone and cortisol) in male patients with severe organic processes (24 chronic and 22 acutely ill) and comparing them with a control group of 15 healthy male subjects or suffering mild processes. Corticoadrenal hormone behaviour in the presence of a severe disease show marked differences between the androgenic and the glucocorticoid pathways. While DHE-S shows a significant decrease in severe disease, independently of the underlying disease (acute or chronic), the contrary occurs with the glucocorticoid pathway, in which cortisol and specially its precursors, progesterone and 17-OH-progesterone, predominantly present in the acute situation, normal or significantly increased levels. These differences between the two adrenal pathways suggest that apart from ACTH there must be another regulatory mechanism of the androgenic pathway which may facilitate the androgenic adaptation to the situation of severe disease.

17-alpha-Hydroxyprogesterone↗
PubMed1989

[Cerebral atrophy in chronic alcoholism].

The brain's morphologic changes induced by chronic abuse of ethanol are studied, using the computerized tomography (CT) of 1005 clinical records reviewed during 1982-1987 at "Hospital Universitario de Granada", only 33 were selected as patients suffering from chronic alcoholism, CTs having been performed. The results were compared with 33 CTs of non-drinking patients. The ventricular index (VI), the evans' index (EI), the transversal diameter of third ventricle (TD) and cerebral sulcus evaluation were the values analysed to estimate the degree of cerebral atrophy. It was proven that a significant decrease of VI, an increase of EI, TD and cerebral sulcus in chronic alcoholic patients exists compared to non-drinkers. 70% of the alcoholic patients had cerebral atrophy. The conclusion of this study is that chronic alcoholism is an important causal factors of the cerebral atrophy process, regardless of age, alcohol intake quantity and/or the existence of other associate pathology.

Adult↗
PubMed1989

[Erythrocyte morphometry in alcoholism].

The aim of this study is to evaluate the erythrocyte morphology (area, perimeter, shape) and its correlation with high alcohol intake and the conventional blood test (MCV, GOT/GPT, and activated PTT). 60 persons were studied (20 non-drinkers, 20 chronic alcoholics and 20 with hepatic cirrhosis). The erythrocyte area and perimeter was significantly higher, in patients other than the group of non-drinkers. This is directly related to the alcohol intake and liver damage. We believe, that the study of the morphology of the erythrocyte is of interest as a "biological marker" related to the grade of alcoholism.

Adult↗
PubMed1989

[The incidence of consumption coagulopathy in liver cirrhosis].

DIC in patients affected by cirrhosis, accompanied by portal hypertension and splenomegaly, has been suspected in the past. The main aim of this study is to ascertain the incidence of this phenomenon. We carried out coagulation and fibrinolytic tests in 113 cirrhotic patients and 20 healthy control persons. We found chronic consumption coagulopathy at analysis level in 28 cases (24.8%) with a decrease of fibrinogen, factor V, kallikrein, platelets, prothrombin complex activity, increase of PDF, partial thromboplastic time and euglobulin lysis. 25 cases had active cirrhosis, with ascites, variceal bleeding and/or hepatic encephalopathy; 3 were non-active cirrhosis. Only 7 patients had clinical DIC. We observed that coagulation disorders increased with more active cirrhosis.

Adult↗