[Late radiogenic injuries with tumor induction following a high-energy one-time irradiation--a follow-up study of over 20 years].
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Biomedical subjects
Publications and source records attributed to J Riedeberger.
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A total of 85 skin biopsies taken from 23 pigs with experimental 3rd-degree burns was tested concerning the efficiency of the synthetic skin substitutes SYSpur-derm (GDR) and Epigard (USA). Both the materials have an excellent wound-cleansing-effect, show good adhesion to the wound surface and have no toxic or antigenic effect.
This publication represents a contribution for the experimental investigation of a suitable skin substitute for temporary covering of vast burns. The synthetic skin substitute SYSpur-derm is a bilaminar polyurethane foam substance. It was tested in the experimental animal pig on skin lesions after third-degree burn and necrectomy. A clean regularly arranged and good vascular granulation tissue was macroscopically and histologically visible on the sixth to the eight day. So favourable conditions were given for the healing up of auto-transplants and it epithelialised partially spontaneously. SYSpur-derm answers the demands on a temporary skin substitute. The synthetic skin substitute offers advantages with regard to the permanent availability, the storage and application, the immunologic inactivity, the sterilisation, and the relatively low cost in face of other materials.
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This study contributes to the experimental investigation of thermic injuries and their metabolic sequels. A model for burns is created in rabbits and normal values determined. Preliminary results are reported for shifts of hemoglobin, hematocrit, and erythrocyte count, as well as for changes in levels of proteins, electrolytes, and blood sugar. The meaning for clinical practics is discussed.
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