[Lactic acid concentration in umbilical venous blood of healthy infants and of those with asphyxia].
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Biomedical subjects
Publications and source records attributed to J Robaczyński.
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Ouabain- and furosemide-dependent rate of sodium outflow through lymphocytes cellular membranes was measured in both healthy pregnant women and those with arterial blood hypertension caused by pregnancy. It was shown, that ouabain-dependent sodium outflow rate is decreased in healthy women in the I, II, and III trimester of pregnancy, while in women with arterial hypertension in the III trimester. No difference in sodium outflow rate both total and furosemide-dependent in healthy pregnant women during the I, II and III trimester, and in pregnant women with arterial hypertension due to pregnancy in the III trimester was noted. No difference in sodium outflow rate was noted in pregnant women with the arterial hypertension due to pregnancy with familial history of the hypertension.
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Dependence of birth weight on insulin dosage in pregnant diabetic women, diabetes mellitus class (according to White) have been discussed. An analysis included 56 pregnancies complicated with diabetes mellitus, which were terminated at the I Department of Obstetrics, Medical Academy in Wrocław between January, 1981 and January, 1988. Neonates birth weight is reversely proportional to insulin daily dose given to pregnant women diabetes mellitus during the III trimester of pregnancy. Diabetic angiopathy and nephropathy could be considered as factors deciding on the low birth weight of neonates delivered by the diabetic mothers despite euglycemia.
The authors, basing in the survey of literature and on own experience, discuss pregnancy in diabetic patients together with possible complications. Pregnancy exerts an unfavourable effect on diabetes mellitus with significant vascular disorders being in some cases even life-threatening. An of clinical status of the diabetes mellitus should be always carefully assessed in every diabetic woman to avoid serious complications, which may occur later-during possible pregnancy. Date of pregnancy termination in every pregnant diabetic with vascular disorders should depend on not only on status of fetus but also of the mother. A chance of getting pregnant in case of diabetic women depends on the advancement of the disease. Persisting vascular and systemic disorders seen in diabetic mellitus are contraindications for pregnancy.
Health status of 53 babies delivered by diabetic mothers are discussed. Neonatal period was uncomplicated only in 12 cases. The remaining babies suffered from respiratory disorders, edema, neurological disturbances, prolonged jaundice, infections etc. Metabolic disorders in diabetic female are unfavourable for the development of pregnancy and neonate health. it may be improved by the proper diagnostico-therapeutical management prior to and during pregnancy and by intensive care of neonates after delivery. It requires, however, the establishment of health institution with highly qualified teams well equipped which will be able to carry out diagnosis and therapy of diabetes mellitus in females in the reproductive age, during pregnancy as well as proper care of the neonates.
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