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Biomedical subjects

J Roda

Publications and source records attributed to J Roda.

15 recordsLinked to original sources
PubMed2003

[Risk factors linked to the transmission of papilloma virus in the school environment. Alicante, 1999].

OBJECTIVE: The aim of this study is to describe an outbreak of plantar warts and to analyse the risk factors wich determining the transmission. DESIGN: Cross-sectional survey. SETTING: A school of Alicante. PARTICIPANTS: 1,620 students. MEASUREMENTS AND MAIN RESULTS: Description and analysis of the outbreak. We studied the magnitude and the association between risk factors (sports activities and hygiene habits) and disease by logistic regression model. We estimated the crudes and adjusted odds ratio (OR) and the confidence intervals (CI) of 95%. We carry out environmental study and active search of cases. The global rate of answer to the cross-secctional survey was 70.86%. Reported cases were 221, the global attack rate was 19.25%. The outbreak occurred over 16 months. We did not find statistical significal difference either by sex (P=.138) or age (P=.233). The hygiene conditions of the swimming pool and the changing room were adapted. The risk of disease increased with the number of activities taking place (P=.001). The OR adjusted for hygiene habits was: use of changing room 0.95 (95% CI, 0.38%-2.41%), use of shower rooms 1.06 (95% CI, 0.70%-1.62%), walking barefoot in the changing room 1.97 (95% CI, 1.39%-2.79%) and showering barefoot 0.97 (95% CI, 0.58%-1.64%). CONCLUSIONS: Outbreak of person to person transmission, the floor of the changing rooms was the prime cause of transmission. We did not find any association between the use of public swimming pool and the disease

Adolescent↗
PubMed2003

Paroxysmal atrial fibrillation prevention by pacing in patients with pacemaker indication.

AIMS: The prevent-atrial fibrillation (AF) registry analyses the clinical relevance and usefulness of the four preventive pacing algorithms, available in a family of cardiac stimulators, to prevent atrial fibrillation. METHODS AND RESULTS: This study is a prospective, non-randomized, multicentre registry. Patients are eligible for the registry if they have sick sinus syndrome (SSS) with or without pre-existing atrial fibrillation. The preventive pacing algorithms were programmed for each patient on an individual basis using the diagnostic features of the devices. In the period from April 2000 to April 2001 a total of 68 patients (33 male, 35 female) has been included in the registry in 14 hospitals in Spain. Mean age was 72+/-12 years and the pacemaker indication was SSS in 15 patients (22%) and SSS with paroxysmal AF in 53 patients (78%). The median AF burden for the total group (n=32) was significantly reduced from 3.9 to 1.3% (67%, P=0.034, Wilcoxon signed rank test). The decrease in AF burden was accompanied by a non-significant decrease in the median number of episodes per day from 1.47 to 0.64 (a decrease of 56%). The average atrial pacing % was increased from 72 to 78%. CONCLUSIONS: The prevent-AF registry demonstrated the usefulness of four preventive pacing algorithms in daily clinical practice. During the registry a significant reduction in AF burden and all other endpoints was observed. Dedicated diagnostics were key to adapting the optimal pacing therapy during follow-up.

Aged↗
PubMed2000

[Prevalence of anti-HAV antibodies and efficacy of pre-vaccine detection at institutions for mentally retarded of the city of Alicante].

OBJECTIVE: The aim of this study was to investigate the prevalence and efficacy of the anti-HAV antibodies detection in institucions for mentally retarded people in the city of Alicante. DESIGN: Prevalence study. SETTING: Two institucions for mentally retarded people in the city of Alicante. PARTICIPANTS: One hundred and seven residents and seventy seven in care of them. MEASUREMENTS AND MAIN RESULTS: We have investigated the anti-HAV antibodies prevalence by enzymeinmunoanalysis of microparticle test. The efficacy of the anti-HAV antibodies detection before the vaccination has been studied by calculating the threshold of prevalence with the following formula: unit cost of detection + (1 - X) x unit cost vaccination anti-HAV negative subjects = unit cost vaccination. RESULTS: The global prevalence of anti-HAV antibodies was 56.5% (95% CI, 49-63.7). The prevalence of the residents was 55.1% (95% CI, 45.2-64.7) and 58.4% in care of them (95% CI, 46.6-69.5). Among the sociodemographic variables evaluated only the age was associated with the prevalence of anti-HAV antibodies (p < 0.001). The unit cost of prevaccination detection of anti-HAV antibodies was calculated as 998 pesetas and the unit cost of the vaccination as 3595, obtaining a prevalence anti-HAV threshold of 27.8%. CONCLUSIONS: The prevalence of anti-HAV antibodies in this collective studied is similar to the prevalence of anti-HAV antibodies of the spaniard population. The direct vaccination without a previous marker study is recommended to people under the age of 31 in this population group.

Adolescent↗
PubMed1999

Bacillus cereus prosthetic valve endocarditis.

Bacillus cereus is a ubiquitous organism that often contaminates microbiological cultures but rarely causes serious infections. Reports of B. cereus endocarditis are infrequent. Infection in patients with valvular heart disease is associated with significant mortality and morbidity. We describe a case of B. cereus endocarditis involving a mechanical mitral prosthesis that resolved after replacement of the prosthetic valve. We also review the previous cases reported in the literature.

Bacillaceae Infections↗
PubMed1999

Pulmonary hydatidosis: surgical treatment and follow-up of 240 cases.

OBJECTIVE: We review a series of 240 patients treated surgically for pulmonary hydatid cyst in our center between 1966 and 1988, assessing the results with our surgical technique, which involves a novel needle aspiration device designed by Professor D. Figuera, and postoperative treatment protocol. PATIENTS AND METHODS: The majority (60.4%) of the patients were from areas endemic for hydatid disease. The mean age of the patients at the time of the surgical procedure was 31.5 +/- 7.2 years (range: 4-70 years). A trocar-suction device was used for the needle aspiration of 276 (92%) of the 300 cysts encountered in the 240 patients. The remaining 24 cysts were removed integrally by means of different surgical techniques such as cyst enucleation, lobectomy, segmentectomy and atypical pulmonary resection. The residual cavity was treated by pericystectomy and eversion to the pleural surface in 238 cases (86.2%) and by capitonnage in 38 (13.7%). High vacuum suction (-30 cm H2O) was employed in every case. Depending on when the procedure was performed, the patients were treated with mebendazole or albendazole according to the protocol designed by Bekhti. RESULTS: Clinical assessment of the symptoms and plain chest X-ray led to the correct diagnosis in 228 cases (95%). In six (2.5%), imaging studies such as ultrasonography, computed tomography and nuclear magnetic resonance were required, and in the remaining six cases (2.5%), the diagnosis was established intraoperatively or in the subsequent histopathological study. One hundred and seventy patients (70.8%) presented a solitary lung cyst, while the remaining 70 (29.2%) were found to have multiple cysts in one or more lobes of one or both lungs. In addition, 45 patients (18.7%) presented hepatic cysts and 25 (10.4%) had cysts in other locations. After 18 years of follow-up, the survival rate was 94.6%. Of the surviving patients, 98.3% were free of pulmonary hydatid disease and 95.1% were free of hydatid disease. CONCLUSIONS: The trocar-suction device employed here for needle aspiration of hydatid cysts has demonstrated its efficacy in preventing the rupture of the cyst and its possible dissemination. With its use, the parasite is eradicated and the residual cavity can be excised.

Adolescent↗
PubMed1994

[The femoral vein route: an exceptional alternative for the implantation of permanent pacemakers].

A case of thrombosis in the superior vena cava after two permanent pacemaker implantations is described. Ten years ago the patient had a permanent pacemaker implanted because of disturbances in his cardiac rhythm. Five months later he was readmitted with pacemaker malfunction due to failure of the electrode and a new lead was introduced. In 1989 the generator presented "end of life" and the depleted battery was changed. In February, 1993 he presented a new pacemaker malfunction and thrombosis in the superior vena cava. We suggest that in similar cases the iliac vein approach should be performed and short-term anticoagulant therapy should be considered.

Arrhythmias, Cardiac↗
PubMed1990

[Experience with dual-chamber pacemakers at the Valencia General Hospital].

We report our experience with dual chamber pacemakers in 70 patients (mean age 64.5), of whom 42 had AV block and 28 sick sinus syndrome, nine of them associated with AV block. Other cardiac disease coexistent with the conduction disturbance was present in 57% of the patients. Follow-up was conducted after implantation at first, 3rd, 6th month, and thereafter each 6 months. Mean follow-up was 20 +/- 14.3 months (2-72); of the 70 patients, 88% and 73% were followed at least for 6 and 12 months, respectively. Six patients (five had AV block) died 17 months on average after implantation. All patients but one had concomitant cardiac disease. Eleven patients (15.6%) presented complications, being all of them related to atrial channel: reprogramming to VVI in five (7%), mainly due to chronic atrial fibrillation (4 patients), whereas in the other one was secondary to loss of pacing and sensing functions; acute dislocation corrected with reoperation in 3 patients (4.3%); temporary loss of atrial sensing in 2 patients, and chronic in the last one, with change to DVI mode. Overall, considering deaths and changes to VVI mode, 15.6% of patients were not be able to maintain dual chamber pacing. In conclusion, our results show: 1) low rate of major complications; 2) good outcome of patients suffering from sick sinus syndrome; 3) the development of chronic atrial fibrillation was the main limitation of DDD pacing system.

Adult↗
PubMed1982

The biocompatibility of polypyrrolidone in test implantation.

The biological compatibility of polypyrrolidone was investigated using subcutaneous implantation in rats. Acute (10 days) and chronic (360 days after implantation) tissue reaction was characterized numerically and compared with poly(2-hydroxyethyl methacrylate), used in the Drug Control Research Institute in Prague as a standard in the evaluation of polymers, for which good tolerance in the clinical practice has been demonstrated. Surface changes in the polymer were evaluated by using a scanning electron microscope.

Animals↗