Primary amyloidosis and syncope.
A 59-year-old caucasian consulted our clinic with symptoms of dizziness and exertional syncope. The combination of myocardial hypertrophy diagnosed by echocardiography, together with a history of peripheral neuropathy made us suspect cardiac amyloidosis which was later proven by endomyocardial biopsy. A graded exercise test and two Holter monitoring studies revealed neither rhythm nor conduction abnormalities. A head-up tilt test revealed a vasovagal vasodepressor response.
Amyloidosis↗