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Biomedical subjects

J Rothenberg

Publications and source records attributed to J Rothenberg.

18 recordsLinked to original sources
PubMed2001

Vaginal bleeding from massive hemoperitoneum. A case report.

BACKGROUND: A gynecology service is often asked to consult and evaluate in-house patients with vaginal bleeding. CASE: A 31-year-old, Asian woman with a history of end-stage renal disease and hemodialysis was admitted to the hospital with a falling hematocrit. She subsequently began to have heavy vaginal bleeding. Computed tomography suggested a peritoneal-cervical fistula. Subsequent exploratory laparotomy documented that the bleeding was caused by retrograde flow of a hemoperitoneum. CONCLUSION: This appears to be the first reported case of retrograde flow from a hemoperitoneum causing vaginal bleeding. Although unusual, this case expands the differential diagnosis when evaluating vaginal bleeding.

Adult↗
PubMed1997

Leg ulceration and the cholesterol embolus.

An important and frequently overlooked cause of leg ulcers are cholesterol emboli. A 79-year-old woman with a non-healing leg ulcer is described. The diagnosis of cholesterol embolism was made with the aid of a deep biopsy of the ulcer and serial sectioning of the specimen. This report serves to illustrate the importance of considering cholesterol embolism when evaluating a chronic leg ulcer, and the diagnostic value of proper biopsy techniques.

Aged↗
PubMed1985

Cutaneous xanthomas associated with chronic myelomonocytic leukemia.

Monocytic leukemia may be associated with specific cutaneous changes in about a third of all cases, most characteristically the plum-colored nodule. Nonspecific cutaneous xanthomas have occasionally been reported with a variety of leukemias, mostly in the pediatric literature, but the first report (to our knowledge) of acute myelomonocytic leukemia presenting with specific cutaneous xanthomatous lesions appeared in 1982. Herein is reported a case of chronic myelomonocytic leukemia presenting with a papular histiocytic eruption, and later showing striking cutaneous xanthomas, together with autopsy findings. Physicians should be aware of this rare but important association.

Adult↗
PubMed1982

Diagnosing tuberculosis by fine-needle aspiration biopsy.

This case report exemplifies the effectiveness of percutaneous fine-needle aspiration biopsy in confirming active pulmonary tuberculosis when conventional methods fail to document the disease. Aspiration biopsy of the suspicious lesion allowed direct examination, which demonstrated acid-fast bacilli. Culture of the aspirate grew Mycobacterium tuberculosis.

Aged↗
PubMed1981

Fine-needle aspiration biopsy with CT guidance.

With computed tomographic guidance, 34 percutaneous fine-needle aspiration biopsies were obtained from various sites in 31 consecutive patients. Biopsy sites included the lung, liver, spleen, pancreas, adrenal glands, kidney, retroperitoneum, pelvis and bony structures. The overall diagnostic accuracy rate was 95 percent. The only complication was a moderate pneumothorax in one patient.

Adult↗
PubMed1980

A novel eosinophil chemotactic factor derived from a histiocytic lymphoma of the central nervous system.

An eosinophil chemotactic activity was identified in extracts of tumour tissue and cerebrospinal fluid from a patient with a histiocytic lymphoma of the brain and spinal cord that was infiltrated extensively with eosinophils and associated with peripheral blood eosinophilia. The histiocytic lymphoma-derived eosinophils chemotactic factor, termed ECF-HL, exhibited a mol. wt of 13,000-14,000 by filtration on Sephadex G-50, was highly acidic based on its elution from a high pressure anion exchange column at pH 2 x 3 - 2 x 1, and was susceptible to inactivation by proteolytic digestion. ECF-HL was absent from extracts of control human brain tissue, glioblastomas, other lymphomas and a variety of carcinomas that lacked an accumulation of eosinophils. Partially purified ECF-HL had no chemokinetic activity, but rendered eosinophils unresponsive to other chemotactic factors. Thus ECF-HL is structurally and functionally distinct from other recognized peptides that are preferentially chemotactic for eosinophils.

Adult↗