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Biomedical subjects

J Rothschild

Publications and source records attributed to J Rothschild.

9 recordsLinked to original sources
PubMed1987

Pancreatoduodenectomy in the management of chronic pancreatitis.

The records of 73 consecutive patients who underwent pancreatoduodenectomy for chronic pancreatitis between 1960 and 1985 were reviewed. The median size of the pancreatic duct was 5 mm. Two operative deaths (2.7%) occurred early in the series. Eighty-eight percent, 86%, and 79% of the patients had improvement in pain at six months, two years, and five years, respectively. Diabetes was present preoperatively in 25% of patients and postoperatively in 37%, 45%, and 69% of patients at six months, two years, and five years, respectively. Pancreatic enzyme preparations were used preoperatively by 26% of patients; this use increased to 75% by five years. Only four of 17 late deaths could be related to diabetes or malnutrition. In most patients, pancreatoduodenectomy achieves long-term pain improvement and permits return to normal activities. Selection of patients is important to decrease the late morbidity and mortality.

Adult↗
PubMed1987

Rapidly fatal pneumococcal septicemia in systemic lupus erythematosus.

Streptococcal pneumoniae septicemia was responsible for the deaths of 3 patients with chronic systemic lupus erythematosus. The absence of a spleen likely contributed to sepsis in 2 patients. One patient had been immunized with 14-valent pneumococcal vaccine with a doubling of serum antibody concentrations at one month to all vaccine capsular polysaccharide types except for Types 1 and 12. The patient died 74 months after immunization of pneumococcal Type 1 sepsis.

Adult↗
PubMed1986

The AIDS virus as an opportunistic organism inducing a state of chronic relative cortisol excess: therapeutic implications.

The AIDS virus is an opportunistic organism which requires a previously immunocompromised host for successful replication. We propose that the primary and as yet unlocalized lesion caused by the AIDS virus involves disruption of physiologically balanced responses to stressors, effectively creating a state of chronic relative cortisol excess. Such a state inhibits successful anti-pathogen strategies including those directed against the AIDS virus itself and leads to a self-sustaining downhill clinical course. Therapies based on this model are discussed.

Acquired Immunodeficiency Syndrome↗
PubMed1980

Temporal arteritis.

Explore the source record for details and available documents.

Adrenal Cortex Hormones↗
PubMed1978

The pediatric corner: the varied manifestations of Crohn's disease in children and adolescents.

Thirty children less than 15 years of age with Crohn's disease are reported. The mean age of onset was nine years and five months. Delay in diagnosis may stem from the varying modes of presentation. The mean delay in diagnosis was two years. Chronic diarrhea and/or recurrent abdominal pain associated with extraintestinal manifestations, particularly abnormalities of growth and development suggests the possibility of Crohn's disease in the pediatric age group. Involvement of the terminal ileum occurred in 29 of the 30 patients. In addition, colonic disease occurred in 13 and jejunal involvement in one. Four patients presented with an acute onset of their disease. A favorable response to either medical or surgical therapy occurred in all four. Twenty-six patients had an insidious onset and tended to have a chronic course despite either medical and/or surgical therapy. Thirteen patients had an intestinal resection, with recurrence occurring in three from 1-4 years postoperatively. To date there has been one death.

Adolescent↗